Inheritance and Genetics of Tourette Syndrome

Tourette Syndrome Genetics: Book Excerpts

Tics - genetics - Tics

Inheritance of Tourette Syndrome:

Autosomal dominant diseases are usually inherited from the one parent who already has the disease. Rare cases of sporadic genetic disease with neither parent having the disease can also occur. See inheritance of autosomal dominant diseases.

Genetics of Tourette Syndrome:

Half of a person's children affected. But severity varies.

Tourette Syndrome: Inheritance and Genetics Details

Inheritance properties of Tourette Syndrome:

Disease inherited from: Usually inherited from one parent who has Tourette Syndrome; see inheritance of autosomal dominant diseases.

Gender bias in inheritance: Male and female children are equally at risk of autosomal dominant diseases.

Inheritance Patterns

Inheritance odds for Tourette Syndrome:

Overall odds of inheritance: Usually inherited from one parent who has Tourette Syndrome; see inheritance of autosomal dominant diseases.

Sibling of diseased child odds of inheriting disease: Usually 50% for autosomal dominant diseases.

Overall odds of inheriting from mother: Usually 50% for autosomal dominant diseases.

Overall odds of inheriting from father: Usually 50% for autosomal dominant diseases.

Mother to son inheritance odds: Usually 50% for autosomal dominant diseases.

Father to son inheritance odds: Usually 50% for autosomal dominant diseases.

Mother to daughter inheritance odds: Usually 50% for autosomal dominant diseases.

Father to daughter inheritance odds: Usually 50% for autosomal dominant diseases.

Inheritance from one diseased parent odds: Usually 50% for autosomal dominant diseases.

Inheritance from two diseased parents odds: Usually 75% (50% disease, 25% double dominant) for autosomal dominant diseases.

Genetic Carriers

Genetic carriers of Tourette Syndrome:

Carriers possible for disease?: No, not for autosomal dominant diseases.

Odds daughter becomes genetic carrier: 0%. There are no carriers for autosomal dominant diseases.

Odds son becomes genetic carrier: 0%. There are no carriers for autosomal dominant diseases.

Inheritance Features

Inheritance features for Tourette Syndrome:

Inheritance pattern: Vertical inheritance for autosomal dominant disease.

Sporadic form of disease possible?: Yes, only one genetic mutation is required for a sporadic version of an autosomal dominant disease.

Double dominant form of disease possible?: Yes, double dominance is definitely applicable for autosomal dominance.

Inheritance from one double dominant parent: Usually 100% inheritance from a double dominant form of an autosomal dominant disease.

About inheritance and genetics:

Inheritance of Tourette Syndrome refers to whether the condition is inherited from your parents or "runs" in families. The level of inheritance of a condition depends on how important genetics are to the disease. Strongly genetic diseases are usually inherited, partially genetic diseases are sometimes inherited, and non-genetic diseases are not inherited. For general information, see Introduction to Genetics.