THROMBOCYTOPENIA

THROMBOCYTOPENIA: Excerpt from Algorithmic Diagnosis of Symptoms and Signs

Ask the Following Questions:

1. What is the WBC count? Thrombocytopenia with a high white count suggests leukemia or myeloid metaplasia. Thrombocytopenia with a normal white count suggests idiopathic thrombocytopenic purpura or drug reaction. Thrombocytopenia with a low white count suggests lupus erythematosus, aplastic anemia, myelofibrosis, drugs, myelophthisic anemia, or pernicious anemia.
2. What is the ANA? A positive ANA in the face of thrombocytopenia and a low white count suggests lupus erythematosus.

DIAGNOSTIC WORKUP

The diagnostic workup should include a CBC, blood smear, sedimentation rate, urinalysis, serum B ₁₂ , chemistry panel, ANA, serum haptoglobins, red cell survival, liver spleen scan, CT scan of the abdomen, and a hematology consult for bone marrow study.

Book Source Details

• Book Title: Algorithmic Diagnosis of Symptoms and Signs
• Author(s): R. Douglas Collins
• Year of Publication: 2003
• Copyright Details: Algorithmic Diagnosis of Symptoms and Signs, Copyright © 2003 Lippincott Williams & Wilkins.

More About Thrombocytopenia

• Back to disease: Thrombocytopenia: Introduction
• Next Book Extract About Thrombocytopenia: Thrombocytopenia (In A Page: Pediatric Signs and Symptoms)
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

More About This Book: Title: Algorithmic Diagnosis of Symptoms and Signs Authors: R. Douglas Collins Publisher: Lippincott Williams & Wilkins Copyright: 2003 ISBN: 0-7817-3805-9

 » Next page: Thrombocytopenia (In A Page: Pediatric Signs and Symptoms)

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