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Symptoms » Weakness » Book Sections
 

Muscle Weakness

Acute or Subacute*
Electrolyte abnormality
   Hyperkalemia
   Hypokalemia
   Hypercalcemia
   Hypermagnesemia
   Hypophosphatemia
Rhabdomyolysis
   Extreme muscular exertion
   Prolonged seizures
   Hyperthermia
   Extensive crush injury or muscle infarction
   Influenza
   Hypokalemia
   Hypophosphatemia
   Alcoholic myopathy
   Snake venoms
   Industrial toxin ingestion
   Familial myoglobinuria
   Metabolic myopathies (e.g., McArdle's disease)
Polymyositis, dermatomyositis
Infection, especially
   Viral
       Influenza
       Coxsackievirus infection
       Rabies
       Poliomyelitis
       Herpes zoster
   Trichinosis
   Toxoplasmosis
   Botulism
   Diphtheria
   Leprosy
   Cysticercosis
   Schistosomiasis
   Trypanosomiasis
   Landry-Guillain-Barré-Strohl syndrome
Peripheral neuropathy, acute
Thyrotoxicosis
Corticosteroid therapy
Organophosphorous poisoning

Chronic


Progressive muscular dystrophies, especially
   Oculopharyngeal
   Duchenne's
   Facioscapulohumeral
   Limb-girdle
   Myotonic
Endocrine disorders
   Hyperthyroidism or hypothyroidism
   Hyperparathyroidism
   Vitamin D deficiency (e.g., vitamin D–deficiency rickets)
   Corticosteroid therapy
   Cushing's syndrome and Addison's disease
   Acromegaly
Connective-tissue disease
   Lupus erythematosus
   Rheumatoid arthritis
   Polymyositis, dermatomyositis
   Sjögren's syndrome
   Mixed connective tissue disease
Alcoholic myopathy
Chronic polymyopathy
   Glycogen storage diseases (e.g., McArdle's disease)
   Central core disease
Mitochondrial myopathy
   Lipid metabolism disorders (e.g., carnitine deficiency)
   Familial periodic paralysis with progressive myopathy
Progressive neural-muscular atrophy
   Amyotrophic lateral sclerosis
   Multiple sclerosis
   Werdnig-Hoffman disease
   Peroneal muscular atrophy (Charcot-Marie-Tooth disease)
   Chronic peripheral neuropathy (e.g., arsenic, lead, nutritional)

Intermittent or Transient, or Both


Electrolyte abnormality
   Hypokalemia
   Hyperkalemia
   Hypophosphatemia
   Hypercalcemia
   Hypermagnesemia
   Hyperkalemic or (sodium channel disorders)
   Hypokalemic periodic paralysis (calcium channel disorders)
Drugs
   Aminoglycosides (especially neomycin, streptomycin, kanamycin, polymyxin B)
   Steroids
   Vincristine, zidovudine, cyclosporin
   Chloroquine
   Bretylium
   Clofibrate, pravastatin, gemfibrozil, niacin, lovastatin
Myasthenia gravis
Eaton-Lambert syndrome
Acute thyrotoxic myopathy
Thyrotoxic periodic paralysis
Paramyotonia congenita
Adynamia episodica hereditaria

References


1. Mendell J, Griggs R, Ptacek L: Diseases of Nerve and Muscle, pp. 2473–2483. See Bibliography, 1.
2. Miller M, Phelps P: Weakness, p. 388. See Bibliography, 2.

*Developing over days to weeks. (See Intermittent or Transient, or Both section)

Book Source Details

  • Book Title: A Pocket Manual of Differential Diagnosis
  • Author(s): Stephen N. Adler, Dianne B. Gasbarra
  • Year of Publication: 1999
  • Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.

Other Book Chapters Related to Weakness

Read excerpts from these other book chapters related to Weakness:

Medical Books Excerpts
  • FATIGUE
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • Fatigue
  • "In a Page: Signs and Symptoms" (2004)
  • Fatigue
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • Fatigue
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Paralysis
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Fatigue
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Paralysis
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Fatigue
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Fatigue
  • "Field Guide to Bedside Diagnosis" (2007)
  • Paralysis
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Fatigue
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Paralysis
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Fatigue
  • "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
  • Fatigue
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • Paralysis
  • "Nursing: Interpreting Signs and Symptoms" (2007)
 

Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 2008 Williams & Wilkins.

More About Causes of Weakness




More About This Book:
Title: A Pocket Manual of Differential Diagnosis
Authors: Stephen N. Adler, Dianne B. Gasbarra
Publisher: Lippincott Williams & Wilkins
Copyright: 1999
ISBN: 0-78171-943-7

 » Next page: Paralysis and Paresis (A Pocket Manual of Differential Diagnosis)

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