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FAILURE TO THRIVE

Failure to thrive is germane to the pediatric patient who is not growing adequately or fails to gain weight and appears emaciated. The physiologic model of intake, absorption, transport, and utilization will help develop a differential diagnosis. Intake. Intake of food may be impaired by social conditions of poverty, malnutrition, and child abuse. It may also be impaired by chronic anxiety and depression or other psychiatric disorders. Finally, the patient may not eat because of a neurologic disorder such as microcephaly, hydrocephalus, cerebral palsy, or other disorders associated with mental retardation . Absorption. Absorption of food may be impaired by malabsorption syndrome and fibrocystic disease. Transport. This topic brings to mind chronic anemia and congenital heart disease especially when associated with hypoxemia. Utilization. Utilization of food is impaired in diabetes mellitus, hypothyroidism, pituitary insufficiency, galactosemia, and uremia. Several chronic infectious diseases are associated with failure to thrive. The child may also come from an abnormal gestation where the mother suffered alcoholism, drug abuse, or chronic illness.

Approach to the Diagnosis

Routine diagnostic workup should include a CBC, sedimentation rate, urinalysis, urine culture, chemistry panel, sweat test, stool for quantitative fat, chest x-ray, and electrocardiogram (ECG). Bone age x-rays are helpful in determining growth retardation. At this point, it is helpful to consult a pediatrician before ordering expensive diagnostic tests.

Other Useful Tests

  1. d-Xylose absorption test (malabsorption syndrome)
  2. Stool for ova and parasites (intestinal parasites)
  3. Serum growth hormone (pituitary insufficiency)
  4. Somatomedin-C level (pituitary insufficiency)
  5. Overnight dexamethasone suppression test (adrenogenital syndrome)
  6. Thyroid profile (myxedema)
  7. CT scan of the brain (hydrocephalus, etc.)
  8. MRI of the brain (hydrocephalus)
  9. Neurology consult
  10. Orthopedic consult
  11. Endocrinology consult
  12. Buccal smear for Barr bodies (Turner syndrome)
  13. Karyotyping (Turner syndrome)

Pictures

FAILURE TO THRIVE - 5744.1.jpg

Book Source Details

  • Book Title: Differential Diagnosis in Primary Care
  • Author(s): R. Douglas Collins MD, FACP
  • Year of Publication: 2007
  • Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2007 Lippincott Williams & Wilkins.

Other Book Chapters Related to Poor feeding

Read excerpts from these other book chapters related to Poor feeding:

Medical Books Excerpts
  • ANOREXIA
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • Anorexia
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • ANOREXIA
  • "Differential Diagnosis in Primary Care" (2007)
  • Anorexia
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Anorexia
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Anorexia
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Anorexia
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Anorexia
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • ANOREXIA
  • "Differential Diagnosis in Primary Care" (2007)
 

Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2008 Williams & Wilkins.

More About Causes of Poor feeding




More About This Book:
Title: Differential Diagnosis in Primary Care
Authors: R. Douglas Collins MD, FACP
Publisher: Lippincott Williams & Wilkins
Copyright: 2007
ISBN: 0-7817-6812-8

 » Next page: Feeding Disorders (The 5-Minute Pediatric Consult)

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