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Sore Throat



Most sore throats and coughs are due to infection. Children may have 5–8 upper respiratory infections per year. The primary differential is between viral and bacterial etiologies, especially group A β-hemolytic streptococcus.

Differential Diagnosis

  • Infectious
    –Viral
         –Adenovirus
         –Rhinovirus
         –Parainfluenza
         –Influenza
         –Coronavirus
         –Others: EBV RSV, CMV, HSV
    –Bacterial
         –Streptococcus
         –Haemophilus
         –Moraxella
         –Staphylococcus
         –Corynebacterium
    –Fungal
         –Candida
    • Inflammatory
      –Allergy
      –Gastroesophageal reflux disease
      –Sinusitis resulting in postnasal drainage
      • Tumors
        –Leukemia
        –Rhabdosarcomas
        –Squamous cell carcinoma secondary to oral ulcerations
      • Trauma
        –Foreign body ingestion
        –Caustic ingestion
        –Soft tissue injury from accidental and nonaccidental trauma
    • Systemic/rheumatologic disorders
      –Kawasaki disease: Mucocutaneous lymph node syndrome may have sore throat at presentation (other oral findings include strawberry tongue, fissured lips, mucosal erythema, fever, and lymphadenopathy)
      –Behçet syndrome
      –Reiter syndrome
      • Others
        –Cigarette smoke
        –Environmental pollutants
        –Pharyngeal drying: Mouth and pharynx can be dry from mouth breathing, more common in the winter months

    Workup and Diagnosis

  • History
    –Duration, onset, severity, frequency, odynophagia, dysphagia, daycare, sick contacts, fever, malaise, headache
    –Foreign body and caustic ingestion
    –Days of school or work missed
    –Immunization history
    –Medical history: Systemic disease, connective tissue disorder
      • Physical exam
        –Nasal exam: Evidence of rhinosinusitis
        –Mouth: Ulcerations, masses, tonsil size, erythema, exudates
        –Neck: Lymphadenopathy
        –Skin: Rash
        –Chest: Wheezes, asymmetry
    • Studies
      –For pharyngitis: A major goal is to differentiate streptococcal pharyngitis from viral etiologies
      –Throat culture: 92% sensitive; 100% specific; requires 24–48 hours
      –Rapid strep test: 72–85% sensitive; 88–100% specific
      –CBC with differential for suspected mononucleosis
      –Chest X-ray (inspiratory and expiratory) for suspected foreign body
      –CT neck: When complication of infection is suspected such as abscess

    Treatment

      • Viral causes
        –Supportive care including hydration, acetaminophen or ibuprofen, bedrest, salt water rinses
        –Steroids may be considered to minimize upper airway obstruction
      • Antibiotics for bacterial etiologies
        –For group A β-hemolytic strep: Shortens duration of symptoms and prevents rheumatic fever
    • Consider inpatient admission when there is concern about adequate airway or oral intake
    • Airway management: Intubation or tracheotomy
    • When gastroesophageal reflux is suspected, treatment may include dietary changes, antireflux therapy
    • Adenotonsillectomy for recurrent tonsillitis is considered depending on frequency of recurrence, i.e., 6–7 infections/year, or 4–5 infections/year for 2 years, or 3 infections/year for 3 years

    Book Source Details

    • Book Title: In A Page: Pediatric Signs and Symptoms
    • Author(s): Jonathan E. Teitelbaum, Kathleen O. Deantonis, Scott Kahan
    • Year of Publication: 2007
    • Copyright Details: In A Page: Pediatric Signs and Symptoms, Copyright © 2007 Lippincott Williams & Wilkins.

    Other Book Chapters Related to Mouth infections

    Read excerpts from these other book chapters related to Mouth infections:

    Medical Books Excerpts
    • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
    • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
    • "In a Page: Signs and Symptoms" (2004)
    • "In a Page: Signs and Symptoms" (2004)
    • "In A Page: Pediatric Signs and Symptoms" (2007)
    • "Differential Diagnosis in Primary Care" (2007)
    • "Differential Diagnosis in Primary Care" (2007)
    • "Handbook of Signs & Symptoms (Third Edition)" (2006)
    • "Handbook of Signs & Symptoms (Third Edition)" (2006)
    • "Professional Guide to Diseases (Eighth Edition)" (2005)
    • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
    • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
    • "Field Guide to Bedside Diagnosis" (2007)
    • "Field Guide to Bedside Diagnosis" (2007)
    • "Handbook of Diseases" (2003)
    • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
    • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
    • "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
    • "Nursing: Interpreting Signs and Symptoms" (2007)
    • "Nursing: Interpreting Signs and Symptoms" (2007)
    • "Differential Diagnosis in Primary Care" (2007)
    • "Differential Diagnosis in Primary Care" (2007)

    Copyright Details: In A Page: Pediatric Signs and Symptoms, Copyright © 2008 Williams & Wilkins.

    More About Causes of Mouth infections




    More About This Book:
    Title: In A Page: Pediatric Signs and Symptoms
    Authors: Jonathan E. Teitelbaum, Kathleen O. Deantonis, Scott Kahan
    Publisher: Lippincott Williams & Wilkins
    Copyright: 2007
    ISBN: 1-4051-0427-9

     » Next page: SORE THROAT (Differential Diagnosis in Primary Care)

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