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1 per 250 - 500 people from Hmong populations in southeast Asia and America suffer from 2-methylbutyryl-coenzyme A dehydrogenase deficiency though many are asymptomatic, Genetics Home Reference website
approx 1 in 249 or 0.40% or 1.1 million people in USA [about data]
WARNING! EXTRAPOLATION ONLY! NOT BASED ON COUNTRY-SPECIFIC DATA SOURCES. The following table attempts to extrapolate the above prevalence rate for 2-methylbutyryl-coenzyme A dehydrogenase deficiency to the populations of various countries and regions. These prevalence extrapolations for 2-methylbutyryl-coenzyme A dehydrogenase deficiency are only estimates, based on applying the prevalence rates from the US (or a similar country) to the population of other countries, and therefore may have very limited relevance to the actual prevalence of 2-methylbutyryl-coenzyme A dehydrogenase deficiency in any region:
| Country/Region | Extrapolated Prevalence | Population Estimated Used |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in North America (Extrapolated Statistics) | ||
| USA | 1,174,621 | 293,655,4051 |
| Canada | 130,031 WARNING! (Details) | 32,507,8742 |
| Mexico | 419,838 WARNING! (Details) | 104,959,5942 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Central America (Extrapolated Statistics) | ||
| Belize | 1,091 WARNING! (Details) | 272,9452 |
| Guatemala | 57,122 WARNING! (Details) | 14,280,5962 |
| Nicaragua | 21,439 WARNING! (Details) | 5,359,7592 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Caribbean (Extrapolated Statistics) | ||
| Puerto Rico | 15,591 WARNING! (Details) | 3,897,9602 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in South America (Extrapolated Statistics) | ||
| Brazil | 736,404 WARNING! (Details) | 184,101,1092 |
| Chile | 63,295 WARNING! (Details) | 15,823,9572 |
| Colombia | 169,243 WARNING! (Details) | 42,310,7752 |
| Paraguay | 24,765 WARNING! (Details) | 6,191,3682 |
| Peru | 110,177 WARNING! (Details) | 27,544,3052 |
| Venezuela | 100,069 WARNING! (Details) | 25,017,3872 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Northern Europe (Extrapolated Statistics) | ||
| Denmark | 21,653 WARNING! (Details) | 5,413,3922 |
| Finland | 20,858 WARNING! (Details) | 5,214,5122 |
| Iceland | 1,175 WARNING! (Details) | 293,9662 |
| Sweden | 35,945 WARNING! (Details) | 8,986,4002 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Western Europe (Extrapolated Statistics) | ||
| Britain (United Kingdom) | 241,082 WARNING! (Details) | 60,270,708 for UK2 |
| Belgium | 41,393 WARNING! (Details) | 10,348,2762 |
| France | 241,696 WARNING! (Details) | 60,424,2132 |
| Ireland | 15,878 WARNING! (Details) | 3,969,5582 |
| Luxembourg | 1,850 WARNING! (Details) | 462,6902 |
| Monaco | 129 WARNING! (Details) | 32,2702 |
| Netherlands (Holland) | 65,272 WARNING! (Details) | 16,318,1992 |
| United Kingdom | 241,082 WARNING! (Details) | 60,270,7082 |
| Wales | 11,672 WARNING! (Details) | 2,918,0002 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Central Europe (Extrapolated Statistics) | ||
| Austria | 32,699 WARNING! (Details) | 8,174,7622 |
| Czech Republic | 4,984 WARNING! (Details) | 1,0246,1782 |
| Germany | 329,698 WARNING! (Details) | 82,424,6092 |
| Hungary | 40,129 WARNING! (Details) | 10,032,3752 |
| Liechtenstein | 133 WARNING! (Details) | 33,4362 |
| Poland | 154,505 WARNING! (Details) | 38,626,3492 |
| Slovakia | 21,694 WARNING! (Details) | 5,423,5672 |
| Slovenia | 8,045 WARNING! (Details) | 2,011,473 2 |
| Switzerland | 29,803 WARNING! (Details) | 7,450,8672 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Eastern Europe (Extrapolated Statistics) | ||
| Belarus | 41,242 WARNING! (Details) | 10,310,5202 |
| Estonia | 5,366 WARNING! (Details) | 1,341,6642 |
| Latvia | 9,225 WARNING! (Details) | 2,306,3062 |
| Lithuania | 14,431 WARNING! (Details) | 3,607,8992 |
| Russia | 575,896 WARNING! (Details) | 143,974,0592 |
| Ukraine | 190,928 WARNING! (Details) | 47,732,0792 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in the Southwestern Europe (Extrapolated Statistics) | ||
| Azerbaijan | 31,473 WARNING! (Details) | 7,868,3852 |
| Georgia | 18,775 WARNING! (Details) | 4,693,8922 |
| Portugal | 42,096 WARNING! (Details) | 10,524,1452 |
| Spain | 161,123 WARNING! (Details) | 40,280,7802 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Southern Europe (Extrapolated Statistics) | ||
| Greece | 42,590 WARNING! (Details) | 10,647,5292 |
| Italy | 232,229 WARNING! (Details) | 58,057,4772 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in the Southeastern Europe (Extrapolated Statistics) | ||
| Albania | 14,179 WARNING! (Details) | 3,544,8082 |
| Bosnia and Herzegovina | 1,630 WARNING! (Details) | 407,6082 |
| Bulgaria | 30,071 WARNING! (Details) | 7,517,9732 |
| Croatia | 17,987 WARNING! (Details) | 4,496,8692 |
| Macedonia | 8,160 WARNING! (Details) | 2,040,0852 |
| Romania | 89,422 WARNING! (Details) | 22,355,5512 |
| Serbia and Montenegro | 43,303 WARNING! (Details) | 10,825,9002 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Northern Asia (Extrapolated Statistics) | ||
| Mongolia | 11,005 WARNING! (Details) | 2,751,3142 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Central Asia (Extrapolated Statistics) | ||
| Kazakhstan | 60,574 WARNING! (Details) | 15,143,7042 |
| Tajikistan | 28,046 WARNING! (Details) | 7,011,556 2 |
| Uzbekistan | 105,641 WARNING! (Details) | 26,410,4162 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Eastern Asia (Extrapolated Statistics) | ||
| China | 5,195,390 WARNING! (Details) | 1,298,847,6242 |
| Hong Kong s.a.r. | 27,420 WARNING! (Details) | 6,855,1252 |
| Japan | 509,332 WARNING! (Details) | 127,333,0022 |
| Macau s.a.r. | 1,781 WARNING! (Details) | 445,2862 |
| North Korea | 90,790 WARNING! (Details) | 22,697,5532 |
| South Korea | 192,935 WARNING! (Details) | 48,233,7602 |
| Taiwan | 90,999 WARNING! (Details) | 22,749,8382 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Southwestern Asia (Extrapolated Statistics) | ||
| Turkey | 275,575 WARNING! (Details) | 68,893,9182 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Southern Asia (Extrapolated Statistics) | ||
| Afghanistan | 114,054 WARNING! (Details) | 28,513,6772 |
| Bangladesh | 565,361 WARNING! (Details) | 141,340,4762 |
| Bhutan | 8,742 WARNING! (Details) | 2,185,5692 |
| India | 4,260,282 WARNING! (Details) | 1,065,070,6072 |
| Pakistan | 636,785 WARNING! (Details) | 159,196,3362 |
| Sri Lanka | 79,620 WARNING! (Details) | 19,905,1652 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Southeastern Asia (Extrapolated Statistics) | ||
| East Timor | 4,077 WARNING! (Details) | 1,019,2522 |
| Indonesia | 953,811 WARNING! (Details) | 238,452,9522 |
| Laos | 24,272 WARNING! (Details) | 6,068,1172 |
| Malaysia | 94,089 WARNING! (Details) | 23,522,4822 |
| Philippines | 344,966 WARNING! (Details) | 86,241,6972 |
| Singapore | 17,415 WARNING! (Details) | 4,353,8932 |
| Thailand | 259,462 WARNING! (Details) | 64,865,5232 |
| Vietnam | 330,651 WARNING! (Details) | 82,662,8002 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in the Middle East (Extrapolated Statistics) | ||
| Gaza strip | 5,299 WARNING! (Details) | 1,324,9912 |
| Iran | 270,012 WARNING! (Details) | 67,503,2052 |
| Iraq | 101,498 WARNING! (Details) | 25,374,6912 |
| Israel | 24,796 WARNING! (Details) | 6,199,0082 |
| Jordan | 22,444 WARNING! (Details) | 5,611,2022 |
| Kuwait | 9,030 WARNING! (Details) | 2,257,5492 |
| Lebanon | 15,108 WARNING! (Details) | 3,777,2182 |
| Saudi Arabia | 103,183 WARNING! (Details) | 25,795,9382 |
| Syria | 72,067 WARNING! (Details) | 18,016,8742 |
| United Arab Emirates | 10,095 WARNING! (Details) | 2,523,9152 |
| West Bank | 9,244 WARNING! (Details) | 2,311,2042 |
| Yemen | 80,099 WARNING! (Details) | 20,024,8672 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Northern Africa (Extrapolated Statistics) | ||
| Egypt | 304,469 WARNING! (Details) | 76,117,4212 |
| Libya | 22,526 WARNING! (Details) | 5,631,5852 |
| Sudan | 156,592 WARNING! (Details) | 39,148,1622 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Western Africa (Extrapolated Statistics) | ||
| Congo Brazzaville | 11,992 WARNING! (Details) | 2,998,0402 |
| Ghana | 83,028 WARNING! (Details) | 20,757,0322 |
| Liberia | 13,562 WARNING! (Details) | 3,390,6352 |
| Niger | 45,442 WARNING! (Details) | 11,360,5382 |
| Nigeria | 71,001 WARNING! (Details) | 12,5750,3562 |
| Senegal | 43,408 WARNING! (Details) | 10,852,1472 |
| Sierra leone | 23,535 WARNING! (Details) | 5,883,8892 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Central Africa (Extrapolated Statistics) | ||
| Central African Republic | 14,969 WARNING! (Details) | 3,742,4822 |
| Chad | 38,154 WARNING! (Details) | 9,538,5442 |
| Congo kinshasa | 233,268 WARNING! (Details) | 58,317,0302 |
| Rwanda | 32,954 WARNING! (Details) | 8,238,6732 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Eastern Africa (Extrapolated Statistics) | ||
| Ethiopia | 285,346 WARNING! (Details) | 71,336,5712 |
| Kenya | 131,928 WARNING! (Details) | 32,982,1092 |
| Somalia | 33,218 WARNING! (Details) | 8,304,6012 |
| Tanzania | 144,283 WARNING! (Details) | 36,070,7992 |
| Uganda | 105,561 WARNING! (Details) | 26,390,2582 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Southern Africa (Extrapolated Statistics) | ||
| Angola | 43,914 WARNING! (Details) | 10,978,5522 |
| Botswana | 6,556 WARNING! (Details) | 1,639,2312 |
| South Africa | 177,793 WARNING! (Details) | 44,448,4702 |
| Swaziland | 4,676 WARNING! (Details) | 1,169,2412 |
| Zambia | 44,102 WARNING! (Details) | 11,025,6902 |
| Zimbabwe | 14,687 WARNING! (Details) | 1,2671,8602 |
| 2-methylbutyryl-coenzyme A dehydrogenase deficiency in Oceania (Extrapolated Statistics) | ||
| Australia | 79,652 WARNING! (Details) | 19,913,1442 |
| New Zealand | 15,975 WARNING! (Details) | 3,993,8172 |
| Papua New Guinea | 21,681 WARNING! (Details) | 5,420,2802 |
WARNING! EXTRAPOLATED STATISTICS ONLY! Not based on data sources from individual countries. These statistics are calculated extrapolations of various prevalence or incidence rates against the populations of a particular country or region. The statistics used for prevalence/incidence of 2-methylbutyryl-coenzyme A dehydrogenase deficiency are typically based on US, UK, Canadian or Australian prevalence or incidence statistics, which are then extrapolated using only the population of the other country. This extrapolation calculation is automated and does not take into account any genetic, cultural, environmental, social, racial or other differences across the various countries and regions for which the extrapolated 2-methylbutyryl-coenzyme A dehydrogenase deficiency statistics below refer to. The extrapolation does not use data sources or statistics about any country other than its population. As such, these extrapolations may be highly inaccurate (especially for developing or third-world countries) and only give a general indication (or even a meaningless indication) as to the actual prevalence or incidence of 2-methylbutyryl-coenzyme A dehydrogenase deficiency in that region. These statistics are presented only in the hope that they may be interesting to some people.
The word 'prevalence' of 2-methylbutyryl-coenzyme A dehydrogenase deficiency usually means the estimated population of people who are managing 2-methylbutyryl-coenzyme A dehydrogenase deficiency at any given time (i.e. people with 2-methylbutyryl-coenzyme A dehydrogenase deficiency). The term 'incidence' of 2-methylbutyryl-coenzyme A dehydrogenase deficiency means the annual diagnosis rate, or the number of new cases of 2-methylbutyryl-coenzyme A dehydrogenase deficiency diagnosed each year (i.e. getting 2-methylbutyryl-coenzyme A dehydrogenase deficiency). Hence, these two statistics types can differ: a short disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.
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