Sclerosing Cholangitis

Sclerosing Cholangitis: Introduction

Scarring and hardening (sclerosis) of bile duct tissues due to a bile duct inflammation (cholangitis). This hardening can damage and block the bile duct, reducing the flow of bile out of the liver. If the blockage is severe, bile backs up into the liver and causes liver damage. The condition progresses slowly and it may be many years or decades before liver failure finally occurs. The condition is more prevalent in men and seems to have genetic and immune system origins. ...more »

Symptoms of Sclerosing Cholangitis

• Fluctuating course of: yellow discolouration of skin and eyes (jaundice)
• Itchy skin (pruritus) and right upper abdominal pain
• Severe intermittent colicky abdominal pain
• Nausea
• Vomiting
• more symptoms...»

See full list of 8 symptoms of Sclerosing Cholangitis

Treatments for Sclerosing Cholangitis

• Antibiotics if cholecystitis (infection of the gall bladder)
• Surgery - stent placement at stricture
• Liver transplantation
• more treatments...»

Read more about treatments for Sclerosing Cholangitis

Wrongly Diagnosed with Sclerosing Cholangitis?

• Misdiagnosis of Sclerosing Cholangitis
• Failure to diagnose Sclerosing Cholangitis
• Hidden causes of Sclerosing Cholangitis (possibly wrongly diagnosed)
• Undiagnosed: Sclerosing Cholangitis

Videos for Sclerosing Cholangitis

See full list of 4 related videos

Sclerosing Cholangitis: Related Patient Stories

• Sclerosing Cholangitis

Sclerosing Cholangitis: Complications

Review possible medical complications related to Sclerosing Cholangitis:

• Cholangiocarcinoma
• more complications...»

Causes of Sclerosing Cholangitis

Read more about causes of Sclerosing Cholangitis.

More information about causes of Sclerosing Cholangitis:

• Sclerosing Cholangitis as a symptom

Disease Topics Related To Sclerosing Cholangitis

Research the causes of these diseases that are similar to, or related to, Sclerosing Cholangitis:

• Chronic liver disease
• Liver cirrhoisis
• Liver failure
• Jaundice
• Ascending cholangitis
• more related diseases...»

Evidence Based Medicine Research for Sclerosing Cholangitis

Medical research articles related to Sclerosing Cholangitis include:

• Antibiotic prophylaxis for GI endoscopy.
• Is there any evidence linking Irritable Bowel Syndrome (IBS) with arthritis?
• Is Campral ok to be used in a chronic alcoholic with abnormal LFTs (eg ALT of 350)?
• Primary sclerosing cholangitis
• Serum and biliary insulin-like growth factor I and vascular endothelial growth factor in determining the cause of obstructive cholestasis.
• Cholangitis
• Cirrhosis
• We have had 4 patients diagnosed with cholangiocarcinoma in the past year, is this high? If so what are the aetiological risk factors?
• more research...»

Click here to find more evidence-based articles on the TRIP Database

Patient Surveys for Sclerosing Cholangitis

• Patient Profile Survey
  Take Survey  View Results
• Survey about the symptoms of your Sclerosing Cholangitis
  Take Survey  View Results

Reseach about Sclerosing Cholangitis

Visit our research pages for current research about Sclerosing Cholangitis treatments.

Clinical Trials for Sclerosing Cholangitis

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Sclerosing Cholangitis include:

• Phase II Pilot Study of Cladribine (2-Chlorodeoxyadenosine; 2-CdA) for Early Stage Primary Sclerosing Cholangitis - This study has been completed (Current: 23 Nov 2006) - cladribine
• Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - budesonide
• Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Trial of High-Dose Urso in Primary Sclerosing Cholangitis - This study has been completed (Current: 23 Nov 2006) - Ursodeoxycholic Acid
• Evaluation of DHA for the Treatment of PSC - This study is currently recruiting patients (Current: 23 Nov 2006) - Docosahexaenoic Acid (DHA)
• more trials...»

See full list of 7 Clinical Trials for Sclerosing Cholangitis

Statistics for Sclerosing Cholangitis

• Medical statistics for Sclerosing Cholangitis
• Prevalence and incidence statistics for Sclerosing Cholangitis
• Death and Mortality statistics for Sclerosing Cholangitis
• Society statistics for Sclerosing Cholangitis

Sclerosing Cholangitis Message Boards

Related forums and medical stories:

• Rare Diseases (143)
  • Adrenal dysfunction?
  • Ross's Syndrome
  • Hashimoto's, Adrenal Problem, Lyme's or Mercury Poisoning?
  • Gitelman's Syndrome, need advise
  • shy-drager need help please
  • More user stories
• Liver Conditions (138)
  • Can Anyone Help Me With Advanced Cirrhosis Of The Liver
  • last stage liver failure
  • Gall Bladder scan showed Fatty Liver...what does this mean?
  • The final stage of liver cirrhosis
  • Liver function blood test question
  • More user stories

User Interactive Forums

Read about other experiences, ask a question about Sclerosing Cholangitis, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Definitions of Sclerosing Cholangitis:

Sclerosing Cholangitis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Sclerosing Cholangitis, or a subtype of Sclerosing Cholangitis, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

 » Next page: What is Sclerosing Cholangitis?

Rate This Website

What do you think about the features of this website? Take our user survey and have your say:

Website User Survey

Medical Tools & Articles:

Next articles:

• What is Sclerosing Cholangitis?
• Prevalence and Incidence of Sclerosing Cholangitis
• Videos related to Sclerosing Cholangitis
• Causes of Sclerosing Cholangitis
• Symptoms of Sclerosing Cholangitis

Tools & Services:

• Bookmark this page
• Symptom Search
• Symptom Checker
• Medical Dictionary
• Give your feedback

Medical Articles:

• Disease & Treatments Search
• Misdiagnosis Center
• Full list of interesting articles

Forums & Message Boards

• Ask or answer a question at the Boards:
• I cannot get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for my condition?
• See all the Boards.