Treatments for Puberty
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Precocious Puberty:
Treatment
(In A Page: Pediatric Signs and Symptoms)
-
Idiopathic TCPP
–No treatment is required if there are no psychological issues and patient is close to pubertal age
–Short stature and psychosocial issues are the potential consequences of withholding treatment
-
TCPP can be treated with GnRH analog
-
Premature adrenarche and thelarche warrant close follow-up
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Removal of adrenal or ovarian/testicular mass if detected
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Treatment of intracranial lesion if diagnosed
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Gonadotropin-independent McCune-Albright syndrome
–Aromatase inhibitors (testolactone) have been tried with some success
-
Psychological support if indicated
» READ BOOK EXCERPT ONLINE »
Source: In A Page: Pediatric Signs and Symptoms, 2007
Precocious puberty in males:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Boys with idiopathic precocious puberty generally require no medical treatment and suffer no physical complications in adulthood. Supportive psychological counseling is the most important therapy.
When precocious puberty is caused by tumors, the outlook is less encouraging. Brain tumors necessitate neurosurgery but may resist treatment and prove fatal. Testicular tumors may be treated by removing the affected testis (orchiectomy). Malignant tumors require chemotherapy and lymphatic radiation therapy. The prognosis is generally good, depending on tumor histology and degree of differentiation.
Adrenogenital syndrome that causes precocious puberty may respond to lifelong therapy with maintenance doses of glucocorticoids (cortisol) to inhibit corticotropin production.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Precocious puberty:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Treatment of constitutional true precocious puberty may include medroxyprogesterone to reduce secretion of gonadotropins and prevent menstruation. Other therapy depends on the cause of precocious puberty and its stage of development:
❑ Adrenogenital syndrome necessitates cortical or adrenocortical steroid replacement.
❑ Abdominal tumors necessitate surgery to remove ovarian and adrenal tumors. Regression of secondary sex characteristics may follow such surgery, especially in young children.
❑ Choriocarcinomas require surgery and chemotherapy.
❑ Hypothyroidism requires thyroid extract or levothyroxine to decrease gonadotropic secretions.
❑ Drug ingestion requires that the medication be discontinued.
In precocious thelarche and pubarche, no treatment is necessary.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
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