What is Progressive Supranuclear Palsy?
What is Progressive Supranuclear Palsy?
- Progressive Supranuclear Palsy: A disorder characterized by reduced motor control, dementia and eye movement problems.
- Progressive Supranuclear Palsy: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
Source - Diseases Database
Progressive Supranuclear Palsy is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Progressive Supranuclear Palsy, or a subtype of Progressive Supranuclear Palsy,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Progressive Supranuclear Palsy as a "rare disease".
Source - Orphanet
Progressive Supranuclear Palsy: Introduction
Types of Progressive Supranuclear Palsy:
Broader types of Progressive Supranuclear Palsy:
How many people get Progressive Supranuclear Palsy?
Prevalance of Progressive Supranuclear Palsy: rare
Who gets Progressive Supranuclear Palsy?
Gender Ratio for Progressive Supranuclear Palsy: males:females 2:1
How serious is Progressive Supranuclear Palsy?
Prognosis of Progressive Supranuclear Palsy: Not fatal. Ongoing disability but lifespan is often normal.
Complications of Progressive Supranuclear Palsy:
see complications of Progressive Supranuclear Palsy
Prognosis of Progressive Supranuclear Palsy:
Although PSP
gets progressively worse, no one dies from PSP itself.
(Source: excerpt from NINDS Progressive Supranuclear Palsy Information Page: NINDS)
...
PSP
gets progressively worse but is not itself directly life-threatening. It
does, however, predispose patients to serious complications such as
pneumonia secondary to difficulty in swallowing (dysphagia).
(Source: excerpt from NINDS Progressive Supranuclear Palsy Information Page: NINDS)
What causes Progressive Supranuclear Palsy?
Causes of Progressive Supranuclear Palsy: see causes of Progressive Supranuclear Palsy
Causes of Progressive Supranuclear Palsy:
The symptoms of PSP are caused by a
gradual deterioration of brain cells in a few tiny but important places at
the base of the brain, in the region called the brainstem.
(Source: excerpt from NINDS Progressive Supranuclear Palsy Information Page: NINDS)
What are the symptoms of Progressive Supranuclear Palsy?
Symptoms of Progressive Supranuclear Palsy:
see symptoms of Progressive Supranuclear Palsy
Complications of Progressive Supranuclear Palsy:
see complications of Progressive Supranuclear Palsy
Onset of Progressive Supranuclear Palsy: 50-70 years
Progressive Supranuclear Palsy: Testing
Diagnostic testing: see tests for Progressive Supranuclear Palsy.
Misdiagnosis: see misdiagnosis and Progressive Supranuclear Palsy.
How is it treated?
Treatments for Progressive Supranuclear Palsy:
see treatments for Progressive Supranuclear Palsy
Research for Progressive Supranuclear Palsy:
see research for Progressive Supranuclear Palsy
Society issues for Progressive Supranuclear Palsy
Hospitalization statistics for Progressive Supranuclear Palsy:
The following are statistics from various sources about hospitalizations and Progressive Supranuclear Palsy:
- 0.0005% (63) of hospital consultant episodes were for progressive supranuclear ophthalmoplegia in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 72% of hospital consultant episodes for progressive supranuclear ophthalmoplegia required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 46% of hospital consultant episodes for progressive supranuclear ophthalmoplegia were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 54% of hospital consultant episodes for progressive supranuclear ophthalmoplegia were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 53% of hospital consultant episodes for progressive supranuclear ophthalmoplegia required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- more statistics...»
Organs Affected by Progressive Supranuclear Palsy:
Organs and body systems related to Progressive Supranuclear Palsy include:
Name and Aliases of Progressive Supranuclear Palsy
Main name of condition: Progressive Supranuclear Palsy
Other names or spellings for Progressive Supranuclear Palsy:
PSP, Nuchal dystonia dementia syndrome, Steele-Richardson-Olszewski syndrome, Familial progressive supranuclear palsy (type)
Nuchal dystonia-dementia syndrome, Progressive supranuclear ophthalmoplegia, Steele-Richardson-Olszewski syndrome
Source - Diseases Database
Familial progressive supranuclear palsy (type), PSP, Steele-Richardson-Olszewski Syndrome, Supranuclear palsy, progressive, Familial progressive supranuclear palsy (type), PSP, Steele-Richardson-Olszewski Syndrome
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)
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