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Diseases » Polyneuropathy » Glossary
 

Glossary for Polyneuropathy

  • Acute intermittent porphyria: A rare metabolic disorder characterized by a deficiency in the porphobilinogen deaminase enzyme which results in a build-up of porphyrins or its precursors in the body. Using certain drugs or eating certain foods can trigger the symptoms of the condition.
  • Alcohol abuse: Excessive use of alcohol ranging from binge drinking to severe alcoholism
  • Burning: When a person willingly harms themselves
  • Chemical poisoning - Ethylene Oxide: Ethylene oxide is a chemical used mainly in detergents, plasticizers, fumigants, inks, cosmetics and brake fluid. Ingestion and other exposures to the chemical can cause various symptoms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure.
  • Chemical poisoning - Jet Fuel-4: Jet Fuel-4 is an aviation turbine fuel used by the US military. Ingestion and other exposures to the chemical can cause various symptoms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure.
  • Chemical poisoning - Trichlorfon: Trichlorfon is an insecticide used mostly in crops. It is considered motderately toxic to humans. Ingestion and other exposures to the chemical can cause various symptoms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure.
  • Choreoacanthocytosis amyotrophic: A rare inherited disease involving neurological degeneration and abnormal red blood cell shape. The disorder progresses slowly and causes involuntary movements, loss of cognitive ability, behavioral changes and seizures.
  • Chronic Kidney Disease: Long-term and generally irreversible disease of the kidneys due to infection, obstruction, congenital diseases or generalised diseases causing failure of the kidneys' normal functions.
  • Connective tissue disorders: Any condition affecting connective tissues.
  • Diabetes: Failing or reduced ability of the body to handle sugars.
  • Familial amyloid polyneuropathy: A rare inherited condition where impaired nerve function is caused by amyloid deposits in peripheral nerves.
  • Hypereosinophilic syndrome: A rare condition where too many eosinophils are produced over an extended period of time for no apparent reason. The eosinophils can infiltrate various organs and tissues and cause dysfunction or damage
  • Lyme disease: Lyme disease is an emerging infectious disease caused by at least three species of bacteria belonging to the genus Borrelia.
  • Multi-centric Castleman's Disease: A rare disorder characterized by a generalized overgrowth of lymph node tissue which forms a tumor-like growth. This form of Castleman's disease is progressive and can be serious.
  • Neuritis: Inflammation of a nerve.
  • POEMS: Very rare plasma cell disorder
  • Porphyria: A group of disorders characterized by excess production of porphyrin or its precursors which affects the skin and/or nervous system.
  • Porphyria, Ala-D: A very rare inherited disorder where involving a lack of the enzyme delta-aminolevulinic acid dehydratase.
  • Possible human carcinogenic exposure - Dacarbazine: Some evidence indicates that exposure to Dacarbazine has a possible link to an increased risk of developing cancer in humans. The carcinogenicity of the substance may be influenced by the duration and level of exposure. Dacarbazine is used as a chemotherapy drug.
  • Pyridoxine deficiency: Deficiency of vitamin B6 which has many uses in the body.
  • Restless Legs Syndrome: A neurological disorder where legs develop and crawling, aching skin sensation which is relived by moving the legs.
  • Spinocerebellar ataxia 12: A rare genetic disorder (chromosome 5q31-q33 defect) characterized by variable symptoms such as arm tremors, gait ataxia and dysarthria (speech disorder) with other.
  • Spinocerebellar ataxia 2: A disorder involving degeneration of the brain and spinal cord and causing progressive coordination difficulty and other symptoms. Symptom generally become more severe earlier than in spinocerebellar ataxia 1.
  • Spinocerebellar ataxia 3: A rare genetic disorder (chromosome 14q32.1defect) characterized by . Gait ataxia and dysarthria (speech disorder) also occur and are symptoms common to all the spinocerebellar ataxia types. The duration of the disease is 1-20 years.
  • Spinocerebellar ataxia, Machado-Joseph type II: A rare genetic disorder (chromosome 14q32.1defect) characterized by intermediate onset of symptoms. Gait ataxia and dysarthria (speech disorder) also occur and are symptoms common to all the spinocerebellar ataxia types.
  • Vitamin B12 Deficiency: A deficiency of Vitamin B12 primarily causes anemias the body is unable to make sufficient quantities of normal red blood cells. Severe cases can lead to permanent nervous system problems. The vitamin B12 deficiency can result from absorption problems, insufficient dietary intake, certain medications (e.g. metformin), inherited conditions (e.g. transcobalamin deficiency) and certain chronic parasitic intestinal infestations.
  • Vitamin deficiency: When there is any deficiency of vitamins in the body
  • Wilson's Disease: Wilson disease, or hepatolenticular degeneration, is a neurodegenerative disease of copper metabolism.


 » Next page: Clinical Trials for Polyneuropathy

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