Clinical Trials for Obstructive sleep apnea

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Obstructive sleep apnea is grouped into the following categories:-

View by trial name

View by drugs used in Obstructive sleep apnea clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Obstructive sleep apnea:

Behavioral Effects of Obstructive Sleep Apnea in Children - This study is no longer recruiting patients (Current: 23 Nov 2006)
Telecommunications System in Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
CEP-10953 in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea (OSA/H) Syndrome - This study has been completed (Current: 23 Nov 2006) - CEP-10953
CEP-10953 for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder - This study is no longer recruiting patients (Current: 23 Nov 2006) - CEP-10953
Treatment of Children With Obstructive Sleep Apnea and Laryngomalacia: the Role of Laser Supraglottoplasty - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of PROVIGIL (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome - This study has been completed (Current: 23 Nov 2006) - Modafinil
Does Caffeine Help Children With Obstructive Sleep Apnea Recover Faster From Anesthesia and With Less Complication After Tonsillectomy and Adenoidectomy? - This study is currently recruiting patients (Current: 23 Nov 2006) - Caffeine (Drug)
A Randomized Study to Compare Polysomnography With Overnight Home Oximetry and Auto CPAP for Sleep Apnea - This study has been completed (Current: 23 Nov 2006)
Effects of Treating Obstructive Sleep Apnea in Epilepsy - This study is no longer recruiting patients (Current: 23 Nov 2006)
CEP-10953 in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea (OSA/H) Syndrome - This study has been completed (Current: 23 Nov 2006) - CEP-10953
Randomized Study of a Simple Weight Loss Program for Obese Patients With Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
The Relation Between OSA and Metabolic Syndrome: Role of Oxidative Stress - This study is currently recruiting patients (Current: 23 Nov 2006)
Polycystic Ovary Syndrome (PCOS) and Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006) - depot leuprolide plus estrogen/progestin replacement,pioglitazone
Study of Effects of Sutures on Results of Palate Surgery for Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Proton Pump Inhibitor Therapy for Mild to Moderate Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006) - Lansoprazole
Mandibular Advancement Device for Obstructive Sleep Apnea - This study has been completed (Current: 23 Nov 2006)
Sleep Apnea Treatment After Stroke (SATS) - This study is currently recruiting patients (Current: 23 Nov 2006)
Markers in Exhaled Breath Condensate in Obstructive Sleep Apnoea (OSA) Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls. - This study has been completed (Current: 23 Nov 2006)
The Role of Clinical Parameters in Predicting the Severity of Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006) - Pantoprazole
Study to Determine the Effectiveness of Pillar Palatal Implants to Treat Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea Before and After Treatment With CPAP. - This study is no longer recruiting patients (Current: 23 Nov 2006)
Early Signs of Atherosclerosis in Obstructive Sleep Apnea: Effects of Treatment - This study has been completed (Current: 23 Nov 2006)
Trial of Effects of Oral Xyrem and Zolpidem on Sleep-Disordered Breathing in Obstructive Sleep Apnea Patients - This study is no longer recruiting patients (Current: 23 Nov 2006) - Xyrem (sodium oxybate) oral solution,Modafinil,Zolpidem
A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate - This study is currently recruiting patients (Current: 23 Nov 2006)
Sleep Disordered Breathing in Children With Single Ventricle Physiology - This study is currently recruiting patients (Current: 23 Nov 2006)
Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
Improvement in Baroreflex Sensitivity in OSAS - This study is currently recruiting patients (Current: 23 Nov 2006)
Down Syndrome and Continuous Positive Pressure Therapy - This study is currently recruiting patients (Current: 23 Nov 2006)
PROVIGIL (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome - This study is no longer recruiting patients (Current: 23 Nov 2006) - Modafinil
Sleep Apnea: Mechanism and Cerebrovascular Consequences - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - acetazolamide
Sleep Disorders Management, Health and Safety in Police - This study is currently recruiting patients (Current: 23 Nov 2006)
Effect of CPAP on Cognitive and Functional Performance in Stroke Patients With Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Comprehensive Police Fatigue Management Program - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
Atrial Fibrillation Recurrence in Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Effectiveness of Auto-Adjusted Continuous Positive Airway Pressure for Long-Term Treatment of Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Study to Evaluate Recovery From Postoperative Pain After Sleep Apnea Surgery - This study is currently recruiting patients (Current: 23 Nov 2006)
Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness - This study is currently recruiting patients (Current: 23 Nov 2006)
Serotonin and the Upper Airway in Obstructive Sleep Apnea - This study has been completed (Current: 23 Nov 2006) - Paroxetine,5HTP
New Pharmacological Treatment for Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006) - mirtazapine
Home Diagnosis and Treatment of Obstructive Sleep Apnea - This study is currently recruiting patients (Current: 23 Nov 2006)
Sleep Apnea in Look AHEAD (Action for Health in Diabetes) - This study is no longer recruiting patients (Current: 23 Nov 2006)
Evaluation of a Mandibular Advancement Device in the Treatment of Obstructive Sleep Apnea Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
Immunological Consequences of Obstructive Sleep Apnea - This study is no longer recruiting patients (Current: 23 Nov 2006)
Vascular Pathophysiology in Obstructive Sleep Apnea - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Allopurinol
The Effect of Lifestyle Intervention Vs Gastric Bypass on Various Comorbidities in Morbidly Obese Subjects - This study is currently recruiting patients (Current: 23 Nov 2006)
The Effect of Positive Airway Pressure on Heart Rate Variability - This study is currently recruiting patients (Current: 23 Nov 2006)
Effect of CPAP on Systemic Blood Pressure, Coagulability and Carotid Intima-Media Thickness in Patients With Sleep Apnoea - This study is currently recruiting patients (Current: 23 Nov 2006)
Effect of Nasal CPAP Blood Pressure and Vascular Endothelial Growth Factor in Obstructive Sleep Apnoea Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
Effect of Endoscopic Gastric Balloon Insertion on Obstructive Sleep Apnea in Patients With Morbid Obesity - This study is currently recruiting patients (Current: 23 Nov 2006)
Comparison Between Auto CPAP and Fixed CPAP in Chinese Patients With OSA - This study has been completed (Current: 23 Nov 2006)
Laparoscopic Adjustable Gastric Banding With Truncal Vagotomy - This study is currently recruiting patients (Current: 23 Nov 2006)
Validation of the ApneaLink Sleep Screener for Obstructive Sleep Apnea (OSA) - This study is currently recruiting patients (Current: 23 Nov 2006)
The Effects of Mometasone Furoate Nasal Spray in Subjects With Mild-Moderate Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) Associated With Perennial Allergic Rhinitis (Study P04726) - This study is currently recruiting patients (Current: 23 Nov 2006) - mometasone furoate nasal spray
Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - omeprazole
Comparison of Automatic CPAP to Fixed CPAP for OSAS Following a Prediction Formula - This study is currently recruiting patients (Current: 23 Nov 2006)
The Use of Oral Appliances as an Adjunct to C-PAP in the Treatment of Obstructive Sleep Apnoea - This study is currently recruiting patients (Current: 23 Nov 2006)
REMStar Auto With C-Flex In-Laboratory Performance v. Conventionally Titrated CPAP Therapy: Performances and Preferences - This study has been completed (Current: 23 Nov 2006)
Polidocanol Sclerotherapy of Pharynges for Obstructive Sleep Apnea (OSA) and Snoring Subjects(SS) - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Polidocanol Sclerotherapy

Drugs used in Clinical Trials for Obstructive sleep apnea

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Obstructive sleep apnea: