The list of treatments mentioned in various sources for Nephrotic syndrome includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.
The first step in getting correct treatment is to get a correct diagnosis. Differential diagnosis list for Nephrotic syndrome may include:
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Note:You must always seek professional medical advice about any prescription drug, OTC drug, medication, treatment or change in treatment plans.
Some of the different medications used in the treatment of Nephrotic syndrome include:
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Source: In a Page: Signs and Symptoms, 2004
Source: In A Page: Pediatric Signs and Symptoms, 2007
The goals of treatment of nephrotic syndrome are to relieve symptoms, prevent complications, and delay progressive kidney damage. Treatment of the causative disorder — possibly lifelong — is necessary to control nephrotic syndrome. Corticosteroid, immunosuppressive, antihypertensive, and diuretic medications may help control symptoms. Antibiotics may be needed to control infections. Angiotensin-converting enzyme inhibitors may significantly reduce the degree of protein loss in urine and are therefore typically prescribed for the treatment of nephrotic syndrome.
Treatment of hypertension and of high cholesterol and triglyceride levels are also recommended to reduce the risk of atherosclerosis and complications. Dietary limitation of cholesterol and saturated fats may be of little benefit because the high levels that accompany this condition seem to result from overproduction by the liver rather than from excessive fat intake. High-protein diets are of debatable value. In many patients, reducing the amount of protein in the diet produces a decrease in urine protein. In most cases, a moderate-protein diet (1 g/kg of body weight per day) is usually recommended. Sodium may be restricted to help control edema. Vitamin D may need to be replaced if nephrotic syndrome is chronic and unresponsive to therapy. Blood thinners may be required to treat or prevent clot formation.
Supportive treatment consists of protein replacement with infusion of salt-poor albumin or with a nutritional diet of 1.5 g protein/kg of body weight, with restricted sodium intake of 0.5 to 1 g/day; diuretics for edema; and antibiotics for infection.
Some patients respond to an 8-week course of corticosteroid therapy (such as prednisone), followed by a maintenance dose. Others respond better to a combination course of prednisone and azathioprine or cyclophosphamide.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Teach the patient how to collect serial urine specimens using the three-glass technique. This technique helps determine whether hematuria marks the beginning, end, or entire course of urination.
Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006
Effective treatment of nephrotic syndrome necessitates correction of the underlying cause, if possible. Supportive treatment consists of protein replacement with a nutritional diet of 1 g protein/kg of body weight, with restricted sodium intake; a diuretic for edema; and an antibiotic for infection. Immunosuppressants, antihypertensives, and diuretics can also help control symptoms. Angiotension-converting enzyme inhibitors can decrease protein loss in urine.
Some patients respond to a course of corticosteroid therapy (such as prednisone), followed by a maintenance dose. Patients with chronic nephrotic syndrome that’s unresponsive to therapy may require vitamin D replacement.
Source: Handbook of Diseases, 2003
Teach the patient how to collect serial urine specimens using the three-glass technique. This technique helps determine whether hematuria marks the beginning, end, or entire course of urination. Encourage the patient to drink plenty of fluids, unless contraindicated.
Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007
▪ Check vital signs frequently.
▪ Monitor intake and output, including the amount and pattern of hematuria.
▪ If the patient has an indwelling urinary catheter in place, ensure its patency and irrigate it if necessary to remove clots and tissue that may impede urine drainage.
▪ Administer prescribed analgesics, and enforce bed rest as indicated.
▪ Prepare the patient for diagnostic tests, such as blood and urine studies, cystoscopy, and renal X-rays or biopsy.
▪ Monitor hemoglobin level and hematocrit; administer blood products as ordered.
▪ Show the patient how to collect urine specimens.
▪ Emphasize the need to increase fluid intake.
▪ Explain the underlying cause of hematuria and its treatment.
Source: Nursing: Interpreting Signs and Symptoms, 2007
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