Epidermal Necrolysis, Toxic

Introduction: Epidermal Necrolysis, Toxic

Description of Epidermal Necrolysis, Toxic

Epidermal Necrolysis, Toxic (medical condition): A skin condition causing widespread blisters to erupt over greater than 30% of the body.

See also:

Toxic epidermal necrolysis:
  »Introduction: Toxic epidermal necrolysis
  »Symptoms of Toxic epidermal necrolysis
  »Causes of Toxic epidermal necrolysis
  »Treatments for Toxic epidermal necrolysis

Epidermal Necrolysis, Toxic: An exfoliative disease of skin seen primarily in adults and characterized by flaccid bullae and spreading erythema so that the skin has the appearance of being scalded. It results primarily from a toxic reaction to various drugs, but occasionally occurs as a result of infection, neoplastic conditions, or other exposure.
Source: MeSH 2007

Epidermal Necrolysis, Toxic: Related Topics

These medical condition or symptom topics may be relevant to medical information for Epidermal Necrolysis, Toxic:

• Epidermal
• Necrolysis
• Toxic

Epidermal Necrolysis, Toxic as a Disease

Epidermal Necrolysis, Toxic: Another name for Toxic epidermal necrolysis (or close medical condition association).
  »Introduction: Toxic epidermal necrolysis
  »Symptoms of Toxic epidermal necrolysis
  »Causes of Toxic epidermal necrolysis
  »Treatments for Toxic epidermal necrolysis

Causes of Epidermal Necrolysis, Toxic

Some of the causes of Epidermal Necrolysis, Toxic are included in the list below:

• Reaction to drugs - in 90% of cases
• Sulfur-containing drugs
• Allopurinol
• Carbemazipine
• Aminopenicillins

Read more about causes of Epidermal Necrolysis, Toxic (Toxic epidermal necrolysis)

Symptoms of Epidermal Necrolysis, Toxic (Toxic epidermal necrolysis)

Some of the symptoms of Epidermal Necrolysis, Toxic incude:

• Skin rash initially red spots that eventually join together
• Sheet-like loss of skin
• Large blisters
• Oozing red patches of skin
• Painful lesions on mucosal surfaces: lips, in mouth, in eyes and on genital and anal skin

See full list of 41 symptoms of Epidermal Necrolysis, Toxic (Toxic epidermal necrolysis)

Treatments for Epidermal Necrolysis, Toxic (Toxic epidermal necrolysis)

Treatments for Epidermal Necrolysis, Toxic (Toxic epidermal necrolysis) include:

• Identify and cease causative drug
• Admission to burns unit/intensive care unit
• Occlusive cutaneous dressings over wounds
• Systemic corticosteroids
• Immunoglobulins given intravenously

See full list of 12 treatments for Epidermal Necrolysis, Toxic

Treatment of Epidermal Necrolysis, Toxic: For more treatment information about Epidermal Necrolysis, Toxic, see treatment of Toxic epidermal necrolysis (Epidermal Necrolysis, Toxic)

Epidermal Necrolysis, Toxic: Related Disease Topics

These medical disease topics may be related to Epidermal Necrolysis, Toxic:

• Lyell's syndrome
• Steven Johnson syndrome
• erythema multiforme
• immunoglobins
• cyclophosphamide
• plasmapheresis
• pentoxyifyline
• N-acetylcysteine
• ulinastatin
• infliximab
• cyclosporin

Terms associated with Epidermal Necrolysis, Toxic:

Terms Similar to Epidermal Necrolysis, Toxic:

• Lyell's Syndrome
• Scalded Skin Syndrome, Nonstaphylococcal

Source - MeSH 2007

Broader terms for Epidermal Necrolysis, Toxic

• Drug Eruptions

Source - MeSH 2007

Hierarchical classifications of Epidermal Necrolysis, Toxic

The following list attempts to classify Epidermal Necrolysis, Toxic into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Skin and Connective Tissue Diseases
  • Skin Diseases
    • Dermatitis
      • Drug Eruptions
        • Epidermal Necrolysis, Toxic

MeSH 2007 Hierarchy

• Immune System Diseases
  • Hypersensitivity
    • Drug Hypersensitivity
      • Drug Eruptions
        • Epidermal Necrolysis, Toxic

MeSH 2007 Hierarchy

• Disorders of Environmental Origin
  • Poisoning
    • Drug Toxicity
      • Drug Eruptions
        • Epidermal Necrolysis, Toxic

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