What is Myelofibrosis?

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What is Myelofibrosis?

Myelofibrosis: A rare condition where progressive scarring or fibrosis of the bone marrow impairs it's ability to make blood cells causing symptoms such as anemia and liver and spleen enlargement.
Myelofibrosis: A partial or complete replacement of the bone marrow stroma by fibrous tissue. It can be a primary bone marrow lesion as part of the chronic myeloproliferative disorders (chronic idiopathic myelofibrosis), a manifestation of acute myeloid leukemia (acute panmyelosis with myelofibrosis), or a secondary phenomenon due to bone marrow involvement by a metastatic tumor (e.g., metastatic breast carcinoma). --2003
Source - Diseases Database
Myelofibrosis: fibrosis of the bone marrow.
Source - WordNet 2.1

Myelofibrosis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Myelofibrosis, or a subtype of Myelofibrosis, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Myelofibrosis: Introduction

How serious is Myelofibrosis?

Prognosis of Myelofibrosis: slowly progressing disease resulting in death in 1-33 years
Complications of Myelofibrosis: see complications of Myelofibrosis

What causes Myelofibrosis?

Causes of Myelofibrosis: see causes of Myelofibrosis

What are the symptoms of Myelofibrosis?

Symptoms of Myelofibrosis: see symptoms of Myelofibrosis

Complications of Myelofibrosis: see complications of Myelofibrosis

Onset of Myelofibrosis: usually 5th decade

Myelofibrosis: Testing

Diagnostic testing: see tests for Myelofibrosis.

Misdiagnosis: see misdiagnosis and Myelofibrosis.

How is it treated?

Treatments for Myelofibrosis: see treatments for Myelofibrosis
Research for Myelofibrosis: see research for Myelofibrosis

Name and Aliases of Myelofibrosis

Main name of condition: Myelofibrosis

Other names or spellings for Myelofibrosis:

Vaughan syndrome, Lewis-Szure syndrome, osteopathia condensans disseminate-myeloid-megakaryocytic-hepatosplenomegaly, chronic nonleukemic myelosis, agnogenic myeloid metaplasia, Idiopathic myelofibrosis, Myeloid metaplasia, Primary myelofibrosis

Agnogenic myeloid metaplasia, Heuck-Assmann disease, Myelosclerosis Source - Diseases Database

Agnogenic myeloid metaplasia, Idiopathic myelofibrosis, Myeloid metaplasia, Primary myelofibrosis
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)