The list of signs and symptoms mentioned in various sources for Machado-Joseph Disease includes the 20 symptoms listed below:
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The disease is characterized by clumsiness and weakness in the arms and legs, spasticity, a staggering lurching gait easily mistaken for drunkenness, difficulty with speech and swallowing, involuntary eye movements, double vision, and frequent urination. Some patients have dystonia (sustained muscle contractions that cause twisting of the body and limbs, repetitive movements, abnormal postures, and/or rigidity) or symptoms similar to those of Parkinson’s disease. Others have twitching of the face or tongue, or peculiar bulging eyes. (Source: excerpt from NINDS Machado-Joseph Disease Information Page: NINDS)
These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
The symptom information on this page attempts to provide a list of some possible signs and symptoms of Machado-Joseph Disease. This signs and symptoms information for Machado-Joseph Disease has been gathered from various sources, may not be fully accurate, and may not be the full list of Machado-Joseph Disease signs or Machado-Joseph Disease symptoms. Furthermore, signs and symptoms of Machado-Joseph Disease may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Machado-Joseph Disease symptoms.
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