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Is there a history of drug ingestion? Many drugs can cause lymphadenopathy; the most notable is Dilantin, but the antibiotics, aspirin, iodides, and certain antihypertensive drugs can cause lymphadenopathy also.
... DIAGNOSTIC WORKUP
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Lymphadenopathy refers to enlargement of the lymph nodes. Localized lymphadenopathy involves one lymph region, whereas generalized lymphadenopathy involves more than one region. More than two thirds of cases of lymphadenopathy in primary care are due to nonspecific causes or... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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Lymphadenopathy, both localized and systemic, is an extremely common presenting symptom encountered by practicing pediatricians. To be considered enlarged, nodes must be at least 1 cm in cervical and axillary regions and
1.5 cm in the inguinal region. Most... Differential Diagnosis ... Workup and Diagnosis ... Treatment
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... Many of the conditions that cause splenomegaly also cause generalized lymphadenopathy. They are best recalled with the use of the mnemonic MINT.
LYMPHADENOPATHY, GENERALIZED
M—
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... Lymphadenopathy — enlargement of one or more lymph nodes — may result from increased production of lymphocytes or reticuloendothelial cells or from infiltration of cells that aren’t normally present. This sign may be generalized ... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Pictures
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... Benign
Infection
Bacterial (any)
Mycobacterial
Bartonella (cat-scratch disease)
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... Primarily a disease of older adults, cancer is second only to cardiovascular disease as the leading cause of death in the United States (more than 560,000 deaths annually). More than 67% of patients who die of cancer are older than age 65. The most common cancers in the United States are... What causes cancer? ... Immune response ... Diagnostic methods ... Staging and grading ... Five major therapies ... Maintaining nutrition and fluid balance ... If the patient can't eat ... Total parenteral nutrition ... Pain control critical ... The hospice approach ... Psychological aspects ... Pictures
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... Non-Hodgkin's lymphomas, also known as malignant lymphomas and lymphosarcomas, are a heterogeneous group of malignant diseases originating in lymph glands and other lymphoid tissue. Nodular lymphomas have a better prognosis than the diffuse form of... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations ... Pictures
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... Malignant spinal neoplasms may be any one of many tumor types similar to intracranial tumors; they involve the cord or its roots and, if untreated, can eventually cause paralysis. As primary tumors, they originate in the meningeal coverings, the parenchyma of the cord or its... Causes and incidence ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Lymphadenopathy—enlargement of one or more lymph nodes—may result from increased production of lymphocytes or reticuloendothelial cells, or from infiltration of cells that aren’t normally present. This sign may be generalized ... History and physical examination ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Pictures
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... Jeffrey D. Harrison
Lymph nodes of abnormal size, consistency, or number define lymphadenopathy. Generalized lymphadenopathy refers to these abnormal nodes when they are found in two or more noncontiguous sites. Generalized lymphadenopathy should prompt further... Approach ... History ... Physical examination ... Testing ... Diagnostic assessment
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... Laeth S. Nasir
Approach In clinical practice, the enlargement of a single lymph node or multiple contiguous lymph nodes is observed most commonly as a reaction to a well-defined process (e.g., impetigo... History ... Physical examination ... Testing ... Diagnostic assessment
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... Differential Overview
Generalized
❑ Infectious mononucleosis
❑ Drugs
❑ Connective tissue disease
❑ HIV infection ... Diagnostic Approach ... Clinical Findings ... Pictures
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... Also known as non-Hodgkin’s lymphomas and lymphosarcomas, malignant lymphomas are a heterogeneous group of malignant diseases originating in lymph glands and other lymphoid tissue. Nodular lymphomas have a better... Causes ... Signs and symptoms ... Diagnosis ... Treatment ... Special considerations
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... Lymphadenopathy — enlargement of one or more lymph nodes — may result from increased production of lymphocytes or reticuloendothelial cells, or from infiltration of cells that aren’t normally present. This sign may be generalized (involving three or more node groups) or... History ... Physical assessment ... Medical causes ... Other causes ... Special considerations ... Pediatric pointers ... Patient counseling ... Pictures
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... Normal lymphnodes are discrete, nontender, and mobile without fixation to underlyingtissues. Normally palpable in cervical, axillary, and inguinal regions. Bamji et al. (1986) reported that normallymph nodes have diameter of 3–12 mm in neonatal periodand 3–16 mm... Principal Causes of Localized Lymphadenopathy ... Clinical Features and Diagnosis: Localized Lymphadenopathy ... Principal Causes of Generalized Lymphadenopathy ... Clinical Features and Diagnosis: Generalized Lymphadenopathy ... Diagnostic Approach ... References
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... Lymphadenopathy—enlargement of one or more lymph nodes—may result from increased production of lymphocytes or reticuloendothelial cells or from infiltration of cells that aren't normally present. This sign may be generalized (involving three or more node groups)... History and physical examination ... Medical causes ... Other causes ... Nursing considerations ... Patient teaching ... Pictures
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Many of the conditions that cause splenomegaly also cause generalized
lymphadenopathy. They are best recalled with the use of the mnemonic
MINT.
M—Malformations include sickle cell anemia and other congenital ... Pictures
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... Author:
Emily Riehm Meier, MD
What to Do - Interpret the Data
TLS is a constellation of metabolic abnormalities that usually occur within
the first 3 to 5 days of starting chemotherapy. Clinicians must be aware that
hydration... Suggested Readings
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... Author:
Cynthia Gibson, MD
What to Do - Interpret the Data
Typhlitis refers to a necrotizing colitis involving the cecum or the cecum
and appendix, and is found in leukemic children. The term neutropenic
enteropathy is also... Suggested Readings
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Harnessing radiation to attack cancer cells is the hottest new therapy in lymphoma treatment. But doctors are still determining when is the best time...
As with any disease, the accurate diagnosis of Lymphoma is crucial to providing the best, most effective treatment for each individual patient. So...
Whether relapsed or refractory, tune in to learn about treatments for indolent non-Hodgkin's lymphoma.
Non-Hodgkin's lymphoma is a complex -- and often confusing -- group of diseases. Tune in for an expert overview of the biology of NHL, as well as...
