Juvenile Paget disease: A rare genetic bone disorder involving abnormal loss of bone mineralization and remineralization, broadened bone shafts and high levels of alkaline phosphatase in the blood. Some juvenile cases are relatively mild. More detailed information about the symptoms, causes, and treatments of Juvenile Paget disease is available below.
See full list of 25 symptoms of Juvenile Paget disease
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Prognosis for Juvenile Paget disease: Bone deformities may be evident by five years of age. The condition becomes progressively severe with many children requiring wheelchairs by the middle of the second decade of life. Milder cases may result in survival past the age of 50 years.
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Juvenile Paget disease is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Juvenile Paget disease, or a subtype of Juvenile Paget disease,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Juvenile Paget disease as a "rare disease".
Source - Orphanet
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