What is Graves Disease?
What is Graves Disease?
- Graves Disease: is an autoimmune disease characterized by hyperthyroidism due to circulating autoantibodies. Thyroid-stimulating immunoglobulins (TSIs) bind to and activate thyrotropin receptors, causing the thyroid gland to grow and the thyroid follicles to increase synthesis of thyroid hormone.
- Graves Disease: Hyperthyroidism associated with diffuse hyperplasia of the thyroid gland (goiter), resulting from production of antibodies that are directed against the thyrotropin receptor complex of the follicular epithelial cells. As a result, the thyroid gland enlarges and secrets increased amounts of thyroid hormones. --2004
Source - Diseases Database
- Graves Disease: exophthalmos occurring in association with goiter; hyperthyroidism with protrusion of the eyeballs.
Source - WordNet 2.1
Graves Disease: Introduction
Types of Graves Disease:
Broader types of Graves Disease:
How many people get Graves Disease?
Prevalance of Graves Disease: 3,048,636 people in the USA 1996 1; 1.3 million people (NWHIC)
Prevalance Rate of Graves Disease: approx 1 in 89 or 1.12% or 3 million people in USA [about data]
Incidence (annual) of Graves Disease: about 5 per 10,000 people (NWHIC)
Incidence Rate of Graves Disease: approx 1 in 2,000 or 0.05% or 136,000 people in USA [about data]
Incidence of Graves Disease: The incidence is about 5 in
10,000 people. (Source: excerpt from Graves' Disease: NWHIC)
Who gets Graves Disease?
Gender Profile for Graves Disease: Women 7:1; ranges from 4:1 to 8:1 (NWHIC)
Gender Ratio for Graves Disease: female:male 8:1
How serious is Graves Disease?
Prognosis of Graves Disease: Most patients become hypothyroid and require replacement. Similarly, the ophthalmopathy generally becomes quiescent. On occasion, hyperthyroidism returns because of persisting thyroid tissue after ablation and high antibody titers of anti-TSI. Further therapy may be necessary in the form of surgery or radioactive iodine ablation.
Complications of Graves Disease:
see complications of Graves Disease
Prognosis of Graves Disease: If left untreated, Graves' disease can be fatal. In most cases,
however, normal health can be restored. (Source: excerpt from Endocrine Diseases: NWHIC)
What causes Graves Disease?
Causes of Graves Disease: see causes of Graves Disease
Risk factors for Graves Disease:
see
risk factors for Graves Disease
What are the symptoms of Graves Disease?
Symptoms of Graves Disease:
see symptoms of Graves Disease
Complications of Graves Disease:
see complications of Graves Disease
Onset of Graves Disease: Graves's disease is the most common cause of hyperthyroidism. Incidence in women reports a rate of 80 cases per 100,000 women per year.
Can anyone else get Graves Disease?
Contagion of autoimmunity:
generally not; see details in contagion of autoimmune diseases.
Graves Disease: Testing
Diagnostic testing: see tests for Graves Disease.
Misdiagnosis: see misdiagnosis and Graves Disease.
How is it treated?
Treatments for Graves Disease:
see treatments for Graves Disease
Prevention of Graves Disease:
see prevention of Graves Disease
Research for Graves Disease:
see research for Graves Disease
Organs Affected by Graves Disease:
Organs and body systems related to Graves Disease include:
Name and Aliases of Graves Disease
Main name of condition: Graves Disease
Class of Condition for Graves Disease: autoimmune
Other names or spellings for Graves Disease:
Graves Hyperthyroidism, Basdow's disease, Basedow disease, exophthalmic goiter, Parry disease, thyrotoxicosis, Hyperthyroid Grave's disease
Basedow's disease
Source - Diseases Database
Graves' disease, Exophthalmic goiter
Source - WordNet 2.1
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» Next page: Online Medical Textbooks for Graves Disease
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