Treatments for Glomerular Disease
Treatments for Glomerular Disease
The list of treatments mentioned in various sources
for Glomerular Disease
includes the following list.
Always seek professional medical advice about any treatment
or change in treatment plans.
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Book Excerpts: Treatment of Glomerular Disease
Treatments of Glomerular Disease: Online Medical Books
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for more information about the treatments of Glomerular Disease.
Hematuria:
Treatment
(In a Page: Signs and Symptoms)
-
Older patients with transient hematuria should always be evaluated due to increased risk of urinary tract cancers; refer to urologist for further evaluation and treatment
-
UTI: Start appropriate antibiotics and follow up with urinalysis to see if hematuria resolves
-
Glomerular sources (RBC casts, protein excretion >500 mg/dL, dysmorphic RBCs): Follow BUN/creatinine, blood pressure, creatinine clearance, and 24-hour urine protein, and refer for biopsy if worsening
-
Nonglomerular source (no RBC casts or dysmorphic RBCs in the urine): Urologic consult if imaging indicates a lesion (renal, bladder, or urethral)
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Stones: Increase hydration, analgesics, urology referral for large or persistent stones
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Myoglobinuria/hemoglobinuria: Treat underlying cause
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Beeturia: Evaluate for iron deficiency or achlorhydria due to pernicious anemia, as treating these disorders may eliminate beeturia; eating foods high in oxalate (spinach, oysters) with beets can also cause beeturia
» READ BOOK EXCERPT ONLINE »
Source: In a Page: Signs and Symptoms, 2004
Hematuria:
Treatment
(In A Page: Pediatric Signs and Symptoms)
-
UTI: Empiric antibiotic (e.g., co-trimoxazole)
-
Manage hypertension
–ACE inhibitors or calcium channel blockers
–Consider diuretics if edematous
-
Suspected acute glomerulonephritis
–Low C3, evidence of recent strep or other infection
–Monitor urine output, weight, BP closely
–Daily outpatient visits until stable
–Inpatient admission if oliguria/edema is severe
–Once acute phase is over, monitor every 1–2 weeks and recheck C3 in 6–8 weeks
-
Nephrolithiasis: Increase fluid intake
–Sodium-restrict (do not calcium-restrict)
–Consult urology for severe pain or obstruction
-
Consult nephrology if hematuria persists or is associated with proteinuria, hypertension, persistently decreased C3, or abnormal creatinine
» READ BOOK EXCERPT ONLINE »
Source: In A Page: Pediatric Signs and Symptoms, 2007
Nephrotic syndrome:
Treatment
(Professional Guide to Diseases (Eighth Edition))
The goals of treatment of nephrotic syndrome are to relieve symptoms, prevent complications, and delay progressive kidney damage. Treatment of the causative disorder — possibly lifelong — is necessary to control nephrotic syndrome. Corticosteroid, immunosuppressive, antihypertensive, and diuretic medications may help control symptoms. Antibiotics may be needed to control infections. Angiotensin-converting enzyme inhibitors may significantly reduce the degree of protein loss in urine and are therefore typically prescribed for the treatment of nephrotic syndrome.
Treatment of hypertension and of high cholesterol and triglyceride levels are also recommended to reduce the risk of atherosclerosis and complications. Dietary limitation of cholesterol and saturated fats may be of little benefit because the high levels that accompany this condition seem to result from overproduction by the liver rather than from excessive fat intake. High-protein diets are of debatable value. In many patients, reducing the amount of protein in the diet produces a decrease in urine protein. In most cases, a moderate-protein diet (1 g/kg of body weight per day) is usually recommended. Sodium may be restricted to help control edema. Vitamin D may need to be replaced if nephrotic syndrome is chronic and unresponsive to therapy. Blood thinners may be required to treat or prevent clot formation.
Supportive treatment consists of protein replacement with infusion of salt-poor albumin or with a nutritional diet of 1.5 g protein/kg of body weight, with restricted sodium intake of 0.5 to 1 g/day; diuretics for edema; and antibiotics for infection.
Some patients respond to an 8-week course of corticosteroid therapy (such as prednisone), followed by a maintenance dose. Others respond better to a combination course of prednisone and azathioprine or cyclophosphamide.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Hematuria:
Patient counseling
(Professional Guide to Signs & Symptoms (Fifth Edition))
Teach the patient how to collect serial urine specimens using the three-glass technique. This technique helps determine whether hematuria marks the beginning, end, or entire course of urination.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006
Nephrotic syndrome:
Treatment
(Handbook of Diseases)
Effective treatment of nephrotic syndrome necessitates correction of the underlying cause, if possible. Supportive treatment consists of protein replacement with a nutritional diet of 1 g protein/kg of body weight, with restricted sodium intake; a diuretic for edema; and an antibiotic for infection. Immunosuppressants, antihypertensives, and diuretics can also help control symptoms. Angiotension-converting enzyme inhibitors can decrease protein loss in urine.
Some patients respond to a course of corticosteroid therapy (such as prednisone), followed by a maintenance dose. Patients with chronic nephrotic syndrome that’s unresponsive to therapy may require vitamin D replacement.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Hematuria:
Patient counseling
(Signs & Symptoms: A 2-in-1 Reference for Nurses)
Teach the patient how to collect serial urine specimens using the three-glass technique. This technique helps determine whether hematuria marks the beginning, end, or entire course of urination. Encourage the patient to drink plenty of fluids, unless contraindicated.
» READ BOOK EXCERPT ONLINE »
Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007
Hematuria:
Nursing considerations
(Nursing: Interpreting Signs and Symptoms)
▪ Check vital signs frequently.
▪ Monitor intake and output, including the amount and pattern of hematuria.
▪ If the patient has an indwelling urinary catheter in place, ensure its patency and irrigate it if necessary to remove clots and tissue that may impede urine drainage.
▪ Administer prescribed analgesics, and enforce bed rest as indicated.
▪ Prepare the patient for diagnostic tests, such as blood and urine studies, cystoscopy, and renal X-rays or biopsy.
▪ Monitor hemoglobin level and hematocrit; administer blood products as ordered.
Patient teaching
▪ Show the patient how to collect urine specimens.
▪ Emphasize the need to increase fluid intake.
▪ Explain the underlying cause of hematuria and its treatment.
» READ BOOK EXCERPT ONLINE »
Source: Nursing: Interpreting Signs and Symptoms, 2007
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