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GLYCOSURIA

GLYCOSURIA: Excerpt from Differential Diagnosis in Primary Care

The finding of glycosuria should prompt one to consider first the conditions that are associated with faulty regulation of the blood sugar and sugar metabolism. First and foremost on that list is diabetes mellitus. However, the differential must include many other endocrine disorders; focusing on the endocrine glands will prompt recall of most of these. Visualizing the pituitary will prompt recall of acromegaly, visualizing the adrenal gland will remind one of Cushing syndrome and pheochromocytoma, and visualizing the thyroid will prompt recall of hyperthyroidism. Finally, visualizing the pancreas will remind one of diabetes mellitus and glucagonoma.


GLYCOSURIA

The clinician should be careful not to forget renal glycosuria (idiopathic or Fanconi syndrome) and starvation in the differential.

Approach to the Diagnosis

The investigation of glycosuria should include a glucose tolerance test, chemistry panel, and electrolyte panel. A clinical history of polyuria, polyphagia, weakness, and weight loss will be helpful. If there are clinical features of one of the endocrine diseases listed above, various tests for these disorders and an endocrinology consult should be ordered.

Other Useful Tests

  1. Free T4 (hyperthyroidism)
  2. T3 assay (hyperthyroidism)
  3. RAI uptake and scan (thyroid adenoma)
  4. Plasma cortisol (Cushing syndrome)
  5. Overnight dexamethasone suppression test (Cushing syndrome)
  6. Serum growth hormone (acromegaly)
  7. Twenty-four–hour urine for catecholamine, VMA, or metanephrine (pheochromocytoma)
  8. Skull x-ray (pituitary adenoma)
  9. CT scan of the brain (acromegaly)
  10. CT scan of the abdomen (pancreatic neoplasm, glucogenoma)

Book Source Details

  • Book Title: Differential Diagnosis in Primary Care
  • Author(s): R. Douglas Collins
  • Year of Publication: 2007
  • Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2007 Lippincott Williams & Wilkins.

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  • GLYCOSURIA
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • POLYDIPSIA
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • Polydipsia
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • Polydipsia
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Polydipsia
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Diabetes Mellitus
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Polydipsia
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Polydipsia
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Polydipsia
  • "Nursing: Interpreting Signs and Symptoms" (2007)
 

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.




More About This Book:
Title: Differential Diagnosis in Primary Care
Authors: R. Douglas Collins
Publisher: Lippincott Williams & Wilkins
Copyright: 2007
ISBN: 0-7817-6812-8

 » Next page: HYPERGLYCEMIA (Differential Diagnosis in Primary Care)

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