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The first priority of treatment is to determine the underlying cause of anemia. Once this is determined, iron replacement therapy can begin. Treatment of choice is an oral preparation of iron or a combination of iron and ascorbic acid (which enhances iron absorption). However, in some cases, iron may have to be administered parenterally — for instance, if the patient is noncompliant to the oral preparation, if he needs more iron than he can take orally, if malabsorption prevents adequate iron absorption, or if a maximum rate of Hb regeneration is desired.
Because total dose I.V. infusion of supplemental iron is painless and requires fewer injections, it’s usually preferred to I.M. administration. Pregnant patients and geriatric patients with severe anemia, for example, should receive a total dose infusion of iron dextran in normal saline solution over 8 hours. To minimize the risk of an allergic reaction to iron, an I.V. test dose of 0.5 ml should be given first. For more patient care information, see Supportive management of patients with anemia, page 1034.
Source: Professional Guide to Diseases (Eighth Edition), 2005
The first priority of treatment is to determine the underlying cause of anemia. When this is determined, iron replacement therapy can begin. The treatment of choice is an oral preparation of iron or a combination of iron and ascorbic acid (which enhances iron absorption). In some cases, iron may have to be administered parenterally — for example, if the patient is noncompliant to the oral preparation, if she needs more iron than she can take orally, if malabsorption prevents adequate iron absorption, or if a maximum rate of Hb regeneration is desired. (See Injecting iron solutions.)
Because a total-dose I.V. infusion of supplemental iron is painless and requires fewer injections, it’s usually preferred over I.M. administration. Pregnant patients and elderly patients with severe anemia, for example, should receive a total-dose infusion of iron dextran in normal saline solution over 8 hours. To minimize the risk of an allergic reaction to iron, an I.V. test dose of 0.5 ml should be given first.
Source: Handbook of Diseases, 2003
Source: The 5-Minute Pediatric Consult, 2008
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