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Blood studies (serum iron levels, total iron-binding capacity, and ferritin levels) and stores in bone marrow may confirm iron deficiency anemia. However, the results of these tests can be misleading because of complicating factors, such as infection, pneumonia, blood transfusion, or iron supplements. Characteristic blood test results include:
❑ low Hb levels (in males, less than 12 g/ dl; in females, less than 10 g/dl)
❑ low hematocrit (in males, less than 39%; in females, less than 35%)
❑ low serum iron levels, with high binding capacity
❑ low serum ferritin levels
❑ low RBC count, with microcytic and hypochromic cells (in early stages, RBC count may be normal, except in infants and children)
❑ decreased mean corpuscular Hb in severe anemia.
Bone marrow studies reveal depleted or absent iron stores (done by staining) and normoblastic hyperplasia.
Diagnosis must rule out other forms of anemia, such as those that result from thalassemia minor, cancer, and chronic inflammatory, hepatic, and renal disease.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Blood studies (serum iron, total iron-binding capacity, and ferritin levels) and stores in bone marrow may confirm iron deficiency anemia. However, the results of these tests can be misleading because of complicating factors, such as infection, pneumonia, blood transfusion, and iron supplements. Characteristic blood study results include:
❑ low Hb levels (males, less than 12 g/dl; females, less than 10 g/dl)
❑ low hematocrit (males, less than 47 ml/dl; females, less than 42 ml/dl)
❑ low serum iron levels, with high iron-binding capacity
❑ low serum ferritin levels
❑ low RBC count, with microcytic and hypochromic cells (in early stages, RBC count may be normal, except in infants and children)
❑ decreased mean corpuscular Hb level (in patients with severe anemia).
Bone marrow studies reveal depleted or absent iron stores (done by staining) and normoblastic hyperplasia.
The diagnosis must rule out other forms of anemia, such as those that result from thalassemia minor, cancer, and chronic inflammatory, liver, and kidney disease.
Source: Handbook of Diseases, 2003
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