| Disease | Prevalence Estimate | US people estimate | Statistic Used for Calculation |
| Autoimmune diseases (overall) |
approx 1 in 31 or 3.13% or 8.5 million people in USA |
8,511,844 |
8,511,845 people in the USA 1996 1
|
| Possibly Autoimmune Diseases |
N/A |
N/A |
No information
|
| Type 1 diabetes |
approx 1 in 800 or 0.12% or 340,000 people in USA |
340,000 |
1-in-800 (NIAID)
|
| rheumatoid arthritis |
approx 1 in 108 or 0.92% or 2.5 million people in USA |
2,499,999 |
2.5 million Americans (NWHIC); 1% of US population (NIAMS)
|
| Autoimmune thyroid diseases |
approx 1 in 50 or 2.00% or 5.4 million people in USA |
5,440,000 |
4 out of 100 women some type of autoimmune thyroid disease
|
| Graves Disease |
approx 1 in 89 or 1.12% or 3 million people in USA |
3,048,636 |
3,048,636 people in the USA 1996 1; 1.3 million people (NWHIC)
|
| Hashimoto's Thyroiditis |
approx 1 in 182 or 0.55% or 1.5 million people in USA |
1,490,371 |
1,490,371 adults and 205,159 children in the USA 1996 1
|
| Systemic Lupus Erythematosus |
approx 1 in 194 or 0.51% or 1.4 million people in USA |
1,400,000 |
1.4 million people in the United States, 1 in 85 (NWHIC)
|
| Multiple Sclerosis |
approx 1 in 700 or 0.14% or 388,571 people in USA |
388,571 |
1-in-700 (NIAID)
|
| Crohn's disease |
approx 1 in 544 or 0.18% or 500,000 people in USA |
499,999 |
500,000 Americans
|
| Psoriasis |
approx 1 in 49 or 2.02% or 5.5 million people in USA |
5,499,999 |
5.5 million people in the USA (NIAMS)
|
| Psoriatic Arthritis |
N/A |
N/A |
No information
|
| Sympathetic ophthalmitis |
N/A |
N/A |
No information
|
| Autoimmune neuropathies |
N/A |
N/A |
No information
|
| Autoimmune oophoritis |
N/A |
N/A |
No information
|
| Autoimmune orchitis |
N/A |
N/A |
No information
|
| Autoimmune Lymphoproliferative Syndrome |
N/A |
N/A |
very rare; NIAID mentions 58 individuals
|
| Antiphospholipid syndrome |
N/A |
N/A |
No information
|
| Sjogren's Syndrome |
approx 1 in 272 or 0.37% or 1 million people in USA |
999,999 |
1 to 4 million people with Sjogren’s Syndrome (NIAMS)
|
| Rheumatoid arthritis |
approx 1 in 108 or 0.92% or 2.5 million people in USA |
2,499,999 |
2.5 million Americans (NWHIC); 1% of US population (NIAMS)
|
| Scleroderma |
approx 1 in 906 or 0.11% or 300,000 people in USA |
300,000 |
estimated 300,000 Americans (NWHIC)
|
| Lupus |
approx 1 in 194 or 0.51% or 1.4 million people in USA |
1,400,000 |
1.4 million people in the United States, 1 in 85 (NWHIC)
|
| Addison's Disease |
approx 1 in 100,000 or 0.00% or 2,720 people in USA |
2,720 |
1 in 100,000; 13,335 people in the USA 1996 1
|
| Polyendocrine deficiency syndrome |
N/A |
N/A |
No information
|
| Polyendocrine deficiency syndrome type 1 |
N/A |
N/A |
No information
|
| Polyendocrine deficiency syndrome type 2 |
N/A |
N/A |
No information
|
| Guillain-Barre Syndrome |
approx 1 in 100,000 or 0.00% or 2,720 people in USA |
2,720 |
about 1 in 100,000 (NWHIC)
|
| Immune Thrombocytopenic Purpura |
N/A |
N/A |
rare.
|
| Pernicious anemia |
approx 1 in 680 or 0.15% or 399,454 people in USA |
399,454 |
399,455 people in the USA 1996 1
|
| Myasthenia Gravis |
approx 1 in 20,000 or 0.00% or 13,600 people in USA |
13,599 |
about 5 per 100,000 to 14 per 100,000 (NWHIC)
|
| Primary biliary cirrhosis |
approx 1 in 29,462 or 0.00% or 9,231 people in USA |
9,231 |
9,232 people in the USA 1996 1
|
| Mixed connective tissue disease |
N/A |
N/A |
No information
|
| Primary Glomerulonephritis |
approx 1 in 4,428 or 0.02% or 61,422 people in USA |
61,422 |
61,423 people with Primary Glomerulonephritis in the USA 1996 1
|
| Vitiligo |
approx 1 in 136 or 0.74% or 2 million people in USA |
1,999,999 |
2 to 5 million people in the USA (1-2% worldwide); 1,059,560 people in the USA 1996 1
|
| Autoimmune uveitis |
approx 1 in 58,658 or 0.00% or 4,637 people in USA |
4,637 |
4,637 people in the USA 1996 1
|
| Autoimmune Hemolytic Anemia |
N/A |
N/A |
No information
|
| Autoimmune Thrombocytopenia |
N/A |
N/A |
No information
|
| Celiac Disease |
approx 1 in 249 or 0.40% or 1.1 million people in USA |
1,088,000 |
1 in 250 Americans estimated rate; actual diagnosis rate is 1 in 4,700 Americans; 1 in 250 in Italy; 1 in 300 in Ireland; 20,000 diagnosed (Reader's Digest Feb 2004)
|
| Dermatitis herpetiformis |
N/A |
N/A |
No information
|
| Autoimmune Hepatitis |
approx 1 in 235,294 or 0.00% or 1,156 people in USA |
1,156 |
1,156 people in the USA 1996 1
|
| Pemphigus |
N/A |
N/A |
No information
|
| Pemphigus Vulgaris |
N/A |
N/A |
No information
|
| Pemphigus Foliaceus |
N/A |
N/A |
No information
|
| Bullous Pemphigoid |
N/A |
N/A |
No information
|
| Autoimmune Myocarditis |
N/A |
N/A |
No information
|
| Autoimmune Vasculitis |
N/A |
N/A |
No information
|
| Autoimmune eye diseases |
N/A |
N/A |
No information
|
| Alopecia Areata |
N/A |
N/A |
No information
|
| Autoimmune Atherosclerosis |
N/A |
N/A |
No information
|
| Behcet's Disease |
N/A |
N/A |
rare in the USA; more common in Middle East, Asia, and Japan.
|
| Autoimmune Myelopathy |
N/A |
N/A |
No information
|
| Autoimmune Hemophilia |
N/A |
N/A |
No information
|
| Autoimmune Interstitial Cystitis |
N/A |
N/A |
No information
|
| Autoimmune Diabetes Insipidus |
N/A |
N/A |
No information
|
| Autoimmune Endometriosis |
N/A |
N/A |
No information
|
| Relapsing Polychondritis |
N/A |
N/A |
No information
|
| Ankylosing Spondylitis |
approx 1 in 775 or 0.13% or 350,879 people in USA |
350,879 |
129 of every 100,000 people in the US (Mayo Clinic)
|
| Autoimmune Urticaria |
N/A |
N/A |
No information
|
| Paraneoplastic Autoimmune Syndromes |
N/A |
N/A |
No information
|
| Dermatomyositis |
approx 1 in 20,205 or 0.00% or 13,461 people in USA |
13,461 |
13,462 people with polymyositis/dermatomyositis in the USA 1996 1
|
| Miller Fisher Syndrome |
N/A |
N/A |
rare
|
| IgA nephropathy |
approx 1 in 4,428 or 0.02% or 61,422 people in USA |
61,422 |
61,423 people in the USA 1996 1
|
| Goodpasture syndrome |
N/A |
N/A |
rare.
|
As a group, however,
autoimmune diseases afflict millions of Americans. (Source: excerpt from
The medical term 'prevalence' of Autoimmune diseases usually refers to the estimated population
of people who are managing Autoimmune diseases at any given time,
whereas the annual diagnosis rate of new cases of Autoimmune diseases is called the 'incidence'.
For more information on prevalence and incidence statistics, see about prevalence and incidence statistics.