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Symptoms of Adrenoleukodystrophy
List of symptoms of Adrenoleukodystrophy:
The list of signs and symptoms mentioned in various sources for Adrenoleukodystrophy includes the 46 symptoms listed below:
- Seizures
- Impaired motor function
- Impaired vision
- Swallowing difficulties
- Attention problems
- Cognitive impairment
- Behavioural impairment
- Adrenal atrophy
- Mental deterioration
- Aphasia
- Apraxia
- Progressive blindness
- Difficulty reading in children
- Difficulty writing in children
- Difficulty understanding speech in children
- Difficulty comprehending written material in children
- Leg stiffness
- Leg weakness
- Urinary disorders
- Adrenocortical insufficiency
- Increased skin pigmentation
- Brain sclerosis
- Brain demyelination
- Seizures
- Lack of control of voluntary leg movements
- Muscle weakness on one side of body
- Hypotension
- Reduced hormone production by testes
- Reduced hormone production by ovaries
- Adrenal insufficiency
- Anemia
- Mental retardation
- Cortical blindness
- Walking difficulty
- Fatigue
- Vomiting
- Aphasia
- Withdrawn state
- Emotional instability
- Aggressive outbursts
- Noncommunicative behavior
- Restlessness
- Abnormal behavior
- Weakness
- Retinal degeneration
- Enlarged liver
Note that Adrenoleukodystrophy symptoms usually refers to various symptoms known to a patient, but the phrase Adrenoleukodystrophy signs may refer to those signs only noticable by a doctor.
More ways to research these symptoms: To research other symptoms use the symptom center, or to research causes of more than one symptom in combination, try our multi-symptom search.
Research More About Adrenoleukodystrophy
Do I have Adrenoleukodystrophy?
- Adrenoleukodystrophy: Introduction
- Adrenoleukodystrophy: Diagnostic Testing to confirm diagnosis
- Home Diagnostic Testing
- How serious is it?
- Treatments for Adrenoleukodystrophy
- More about Adrenoleukodystrophy
Home Diagnostic Testing
Home medical tests related to Adrenoleukodystrophy:
- Fatigue: Related Home Tests:
- Adrenal Gland Health: Home Testing:
More about symptoms of Adrenoleukodystrophy:
More information about symptoms of Adrenoleukodystrophy and related conditions:
- Tests to determine if these are the symptoms of Adrenoleukodystrophy
- Symptoms that may be caused by complications of Adrenoleukodystrophy
- Underlying causes of Adrenoleukodystrophy
Other Possible Causes of these Symptoms
Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.
- Abnormal behavior - see all causes of Behavioral symptoms
- Adrenal atrophy - see all causes of Adrenal gland symptoms
- Adrenal insufficiency - see all causes of Adrenal gland symptoms
- Aggressive outbursts - see all causes of Aggression
- Anemia - see all causes of Anemia
- Aphasia - see all causes of Aphasia
- Aphasia - see all causes of Aphasia
- Apraxia - see all causes of Apraxia
- Behavioural impairment - see all causes of Behavioral symptoms
- Brain demyelination - see all causes of Brain symptoms
- Brain sclerosis - see all causes of Brain symptoms
- Cognitive impairment - see all causes of Cognitive impairment
- Enlarged liver - see all causes of Enlarged liver
- Fatigue - see all causes of Fatigue
- Hypotension - see all causes of Low blood pressure
- Impaired vision - see all causes of Impaired vision
- Increased skin pigmentation - see all causes of Increased skin pigmentation
- Leg stiffness - see all causes of Stiff leg
- Leg weakness - see all causes of Leg weakness
- Mental deterioration - see all causes of Cognitive impairment
- Mental retardation - see all causes of Mental retardation
- Muscle weakness on one side of body - see all causes of Muscle weakness
- Reduced hormone production by ovaries - see all causes of Ovary symptoms
- Reduced hormone production by testes - see all causes of Testicle symptoms
- Restlessness - see all causes of Restlessness
- Retinal degeneration - see all causes of Retinal degeneration
- Seizures - see all causes of Seizures
- Seizures - see all causes of Seizures
- Swallowing difficulties - see all causes of Dysphagia
- Vomiting - see all causes of Vomiting
- Walking difficulty - see all causes of Walking symptoms
- Weakness - see all causes of Weakness
Medical Books Online about Adrenoleukodystrophy
Medical Books Excerpts Excerpts of published medical book chapters related to Adrenoleukodystrophy are available from published medical books for more detailed information about Adrenoleukodystrophy.
- "Professional Guide to Signs & Symptoms (Fifth Edition)"
- [ read ]
Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
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Symptoms of Adrenoleukodystrophy: Online Medical Books
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the symptoms of Adrenoleukodystrophy.
Adrenal crisis:
Signs and Symptoms
(Professional Guide to Diseases (Eighth Edition))
Profound weakness, nausea, vomiting, hypotension, dehydration, high fever followed by hypothermia, vascular collapse, renal shutdown, coma
Adrenal hypofunction:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Adrenal hypofunction typically produces such effects as weakness, fatigue, weight loss, and various GI disturbances, such as nausea, vomiting, anorexia, and chronic diarrhea. When primary, the disorder usually causes a conspicuous bronze coloration of the skin. The patient appears to be deeply suntanned, especially in the creases of the hands and over the metacarpophalangeal joints, the elbows, and the knees. He may also exhibit a darkening of scars, areas of vitiligo (absence of pigmentation), and increased pigmentation of the mucous membranes, especially the buccal mucosa. Abnormal skin and mucous membrane coloration results from decreased secretion of cortisol (one of the glucocorticoids), which causes the pituitary gland to simultaneously secrete excessive amounts of corticotropin and melanocyte-stimulating hormone (MSH).
Associated cardiovascular abnormalities in adrenal hypofunction include orthostatic hypotension, decreased cardiac size and output, and a weak, irregular pulse. Other clinical effects include decreased tolerance for even minor stress, poor coordination, fasting hypoglycemia (due to decreased gluconeogenesis), and a craving for salty food. Adrenal hypofunction may also retard axillary and pubic hair growth in females, decrease the libido (from decreased androgen production) and, in severe cases, cause amenorrhea.
Secondary adrenal hypofunction produces similar clinical effects but without hyperpigmentation because corticotropin and MSH levels are low. Because aldosterone secretion may continue at fairly normal levels in secondary adrenal hypofunction, this condition doesn’t necessarily cause accompanying hypotension and electrolyte abnormalities.
Early signs and symptoms of mental impairment may include slowness in thinking, difficulty concentrating, impaired judgment, and memory loss. Dementia is progressive and occurs early. Involuntary movements, such as muscle twitching, trembling, and peculiar body movements, and visual disturbances, appear with disease progression and advancing mental deterioration. Hallucinations are also common. Duration of the typical illness is 4 months.
Sudden onset of fever, headache, vomiting, meningeal irritation (stiff neck and back), drowsiness, coma, paralysis, seizures, ataxia, psychoses
Mild infections of the virus are more common and include fever, headache, and body aches, usually accompanied by a skin rash and swollen lymph glands. Severe infections can be manifested by headache, high fever, neck stiffness, stupor, disorientation, coma, tremors, occasional convulsions, paralysis and, rarely, death.
The incubation period for West Nile encephalitis is anywhere from 5 to 15 days after exposure. Most patients who are bitten by an infected mosquito won’t develop symptoms. It's estimated that only 1 in 300 people who are bitten by an infected mosquito will actually get sick.
Signs and symptoms vary with the type of adrenal hypofunction.
Addison’s disease typically produces weakness, fatigue, weight loss, nausea, vomiting, and anorexia. Asthenia (constant fatigue) is the cardinal symptom, most evident in times of stress.
The disorder also usually causes a conspicuous bronze coloration of the skin. The patient appears to be deeply suntanned, especially in the creases of the hands and over the metacarpophalangeal joints, the elbows, and the knees. He also may exhibit a darkening of scars, areas of vitiligo (absence of pigmentation), and increased pigmentation of the mucous membranes, especially the buccal mucosa. Such abnormal skin and mucous membrane coloration results from decreased secretion of cortisol (a glucocorticoid), which causes the pituitary gland to simultaneously secrete excessive amounts of corticotropin and melanocyte-stimulating hormone (MSH).
Associated cardiovascular abnormalities include orthostatic hypotension, decreased cardiac size and output, and a weak, irregular pulse.
Other signs and symptoms include decreased tolerance for even minor stress, fasting hypoglycemia (due to decreased gluconeogenesis), and a craving for salty food due to decreased mineralocorticoid secretion, which normally causes salt retention.
GENDER INFLUENCE: In women with adrenal hypofunction, androgen levels are low, though they may be treated with daily replacement of 25 to 50 mg of dehydroepiandrosterone to improve quality of life and skeletal density. Also, axillary and pubic hair may be decreased due to loss of adrenal androgens. Secondary hypofunction produces signs and symptoms similar to those of primary hypofunction but without hyperpigmentation because corticotropin and MSH levels are low. Because aldosterone secretion may continue at fairly normal levels in those with secondary adrenal hypofunction, this condition doesn’t necessarily cause accompanying hypotension and electrolyte abnormalities.
Besides producing profound weakness, adrenal crisis also causes fatigue, nausea, vomiting, hypotension, dehydration and, occasionally, high fever followed by hypothermia. If untreated, this condition can ultimately lead to vascular collapse, renal shutdown, coma, and death.
Early signs and symptoms of mental impairment may include slowness in thinking, difficulty concentrating, impaired judgment, and memory loss. Dementia is progressive and occurs early. With disease progression and mental deterioration, involuntary movements, such as muscle twitching, trembling, and peculiar body movements, and vision disturbances appear. Hallucinations also are common. Duration of the typical illness is 4 months.
All viral forms of encephalitis have similar clinical features, although certain differences do occur.
Usually, the acute illness begins with sudden onset of fever, headache, and vomiting and progresses to include signs and symptoms of meningeal irritation (stiff neck and back) and neuronal damage (drowsiness, coma, paralysis, seizures, ataxia, and organic psychoses). After the acute phase of the illness, coma may persist for days or weeks.
The severity of arbovirus encephalitis may range from subclinical to rapidly fatal necrotizing disease. Herpes encephalitis also produces signs and symptoms that vary from subclinical to acute and commonly fatal fulminating disease. Associated effects include disturbances of taste or smell.
Mild WNV infections are more common than severe infections and include symptoms such as fever, headache, and body aches, often accompanied by swollen lymph glands and a skin rash. Severe infections present with symptoms such as headache, high fever, neck stiffness, stupor, disorientation, coma, tremors, occasional convulsions, paralysis and, rarely, death.
The incubation period for West Nile encephalitis is 5 to 15 days after exposure.
CLINICAL TIP: Researchers estimate that only 1 in 300 people who are bitten by a mosquito infected with WNV actually develops the disease.
When considering symptoms of Adrenoleukodystrophy, it is also important to consider Adrenoleukodystrophy as a possible cause of other medical conditions.
The Disease Database lists the following medical conditions that Adrenoleukodystrophy may cause:
Creutzfeldt-Jakob disease:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Encephalitis:
Signs and Symptoms
(Professional Guide to Diseases (Eighth Edition))
West Nile encephalitis:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Adrenal hypofunction:
Signs and symptoms
(Handbook of Diseases)
Primary hypofunction
Secondary hypofunction
Adrenal crisis
Creutzfeldt-Jakob disease:
Signs and symptoms
(Handbook of Diseases)
Encephalitis:
Signs and symptoms
(Handbook of Diseases)
West Nile encephalitis:
Signs and symptoms
(Handbook of Diseases)
Adrenoleukodystrophy as a Cause of Symptoms or Medical Conditions
- (Source - Diseases Database)
Medical articles and books on symptoms:
These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:
- Diagnostic Testing for a Diagnosis of Adrenoleukodystrophy
- How serious is Adrenoleukodystrophy?
- More about Adrenoleukodystrophy
- Online Diagnosis
- Self Diagnosis Pitfalls
- Pitfalls of Online Diagnosis
- Symptoms of the Silent Killer Diseases
- Lesser known silent killer diseases
- Books on signs and symptoms
Full list of premium articles on symptoms and diagnosis
About signs and symptoms of Adrenoleukodystrophy:
The symptom information on this page attempts to provide a list of some possible signs and symptoms of Adrenoleukodystrophy. This signs and symptoms information for Adrenoleukodystrophy has been gathered from various sources, may not be fully accurate, and may not be the full list of Adrenoleukodystrophy signs or Adrenoleukodystrophy symptoms. Furthermore, signs and symptoms of Adrenoleukodystrophy may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Adrenoleukodystrophy symptoms.
» Next page: Diagnostic Tests for Adrenoleukodystrophy
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- Diagnostic Tests for Adrenoleukodystrophy
- Diagnosis of Adrenoleukodystrophy
- Signs of Adrenoleukodystrophy
- Complications of Adrenoleukodystrophy
- Misdiagnosis of Underlying Causes of Adrenoleukodystrophy
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