Diseases » Adrenoleukodystrophy » Summary

What is Adrenoleukodystrophy?

Contents

Adrenoleukodystrophy: Introduction
Types of Adrenoleukodystrophy
Prognosis
Complications
Prevalence
Other names for Adrenoleukodystrophy
What causes Adrenoleukodystrophy?
What are the symptoms of Adrenoleukodystrophy?
Organs Affected by Adrenoleukodystrophy
Can anyone else get Adrenoleukodystrophy?
How is it treated?
Adrenoleukodystrophy: Introduction

What is Adrenoleukodystrophy?

Adrenoleukodystrophy: A rare disorder which has characteristic symptoms of Addison disease (adrenocortical insufficiency) and Schilder disease (cerebral sclerosis). Bronze skin, brain sclerosis and demyelination are the main symptoms.
Adrenoleukodystrophy: A syndrome combining the characteristics of adrenocortical insufficiency (Addison disease) with those of cerebral sclerosis (Schilder disease). Skin bronzing and sclerosis of the brain and demyelination are the principal manifestations.
Source - Diseases Database

Adrenoleukodystrophy is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Adrenoleukodystrophy, or a subtype of Adrenoleukodystrophy, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Adrenoleukodystrophy: Introduction

Types of Adrenoleukodystrophy:

Types of Adrenoleukodystrophy:

Classic childhood ALD - severe form in boys
Adult-onset ALD - milder form in young adults
Female carrier ALD - mild form in female carrying the gene.
Neonatal ALD
more types...»

Broader types of Adrenoleukodystrophy:

How many people get Adrenoleukodystrophy?

Prevalance of Adrenoleukodystrophy: 1 per 20,000 people suffer from X-linked adrenoleukodystrophy, Genetics Home reference website
Prevalance Rate of Adrenoleukodystrophy: approx 1 in 20,000 or 0.00% or 13,600 people in USA [about data]

How serious is Adrenoleukodystrophy?

Complications of Adrenoleukodystrophy: see complications of Adrenoleukodystrophy
Prognosis of Adrenoleukodystrophy: Prognosis for patients with ALD is generally poor except after successful bone marrow transplantation. Death may occur within 1 to 10 years after the onset of symptoms due to disease progression. (Source: excerpt from NINDS Adrenoleukodystrophy Information Page: NINDS)

What causes Adrenoleukodystrophy?

Causes of Adrenoleukodystrophy: see causes of Adrenoleukodystrophy

What are the symptoms of Adrenoleukodystrophy?

Symptoms of Adrenoleukodystrophy: see symptoms of Adrenoleukodystrophy

Complications of Adrenoleukodystrophy: see complications of Adrenoleukodystrophy

Can anyone else get Adrenoleukodystrophy?

Contagion of genetic conditions: generally not; see details in contagion of genetic diseases.

Inheritance of genetic conditions: see details in inheritance of genetic diseases.

Adrenoleukodystrophy: Testing

Diagnostic testing: see tests for Adrenoleukodystrophy.

Misdiagnosis: see misdiagnosis and Adrenoleukodystrophy.

How is it treated?

Treatments for Adrenoleukodystrophy: see treatments for Adrenoleukodystrophy
Prevention of Adrenoleukodystrophy: see prevention of Adrenoleukodystrophy
Research for Adrenoleukodystrophy: see research for Adrenoleukodystrophy

Organs Affected by Adrenoleukodystrophy:

Organs and body systems related to Adrenoleukodystrophy include:

Name and Aliases of Adrenoleukodystrophy

Main name of condition: Adrenoleukodystrophy

Class of Condition for Adrenoleukodystrophy: genetic

Other names or spellings for Adrenoleukodystrophy:

Addison-Schilder disease, ALD, Simerling-Creutzfeldt, Addison-Scholz, Addison-Schilder, bronze syndrome, melanodermic leukodystrophy, sudanophilic leukodystrophy [bronzing of skin - adrenal atrophy], Addison disease [spastic paraplegia syndrome], Fanconi-Prader syndrome, Siemerling-Creutzfeldt syndrome, adrenocortical atrophy [cerebral sclerosis syndrome], bronze Schilder disease, Addison disease with cerebral sclerosis, encephalitis periaxialis diffusa, Flatau-Schilder disease, Myelinoclastic diffuse sclerosis, X-linked adrenoleukodystrophy, AMN, Adrenomyeloneuropathy, Siemerling-Creutzfeldt disease, Addison disease and cerebral sclerosis

Adrenomyeloneuropathy, Bronze Schilder disease, Siemerling-Creutzfeldt disease, Adrenoleucodystrophy, Addison-Schilder syndrome Source - Diseases Database

AMN, Addison disease and cerebral sclerosis, Addison-Schilder syndrome, Adrenomyeloneuropathy, Bronze Schilder disease, Schilder's disease, Siemerling-Creutzfeldt disease, Adrenomyeloneuropathy, Bronze Schilder disease, Schilder's disease, Siemerling-Creutzfeldt disease, AMN, Addison disease and cerebral sclerosis, X-linked adrenoleukodystrophy, Adrenoleukodystrophy, X-linked
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)