Acrodermatitis Enteropathica is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Acrodermatitis Enteropathica, or a subtype of Acrodermatitis Enteropathica, affects less than 200,000 people in the US population.
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Zinc deficiency usually results from excessive intake of foods (containing iron, calcium, vitamin D, and the fiber and phytates in cereals) that bind zinc to form insoluble chelates that prevent its absorption. Occasionally, it results from blood loss due to parasitism and low intake of foods containing zinc. Alcohol and corticosteroids increase renal excretion of zinc.
Zinc deficiency is most common in people from underdeveloped countries, especially in the Middle East. Children are most susceptible to this deficiency during periods of rapid growth.
Source: Professional Guide to Diseases (Eighth Edition), 2005
The term 'prevalence' of Acrodermatitis Enteropathica usually refers to the estimated population of people who are managing Acrodermatitis Enteropathica at any given time. The term 'incidence' of Acrodermatitis Enteropathica refers to the annual diagnosis rate, or the number of new cases of Acrodermatitis Enteropathica diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.
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