The list of signs and symptoms mentioned in various sources for Acquired agranulocytosis includes the 8 symptoms listed below:
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Characteristically, patients with granulocytopenia experience slowly progressive fatigue and weakness; however, if they develop an infection, they can exhibit sudden onset of fever and chills and mental status changes. Overt signs of infection (pus formation) are usually absent. Localized infection can quickly become systemic (bacteremic) or spread throughout an organ (pneumonia). All patients should be meticulously evaluated for even subtle signs of infection because untreated infections can lead to septic shock in 8 to 24 hours. If granulocytopenia results from an idiosyncratic drug reaction, signs of infection develop abruptly, without slowly progressive fatigue and weakness.
Patients with lymphocytopenia may exhibit enlarged lymph nodes, spleen, and tonsils and signs of an associated disease.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Patients with granulocytopenia typically experience slowly progressive fatigue and weakness, followed by the sudden onset of signs of overwhelming infection (fever, chills, tachycardia, anxiety, headache, and extreme prostration); ulcers in the mouth or colon; pharyngeal ulceration, possibly with associated necrosis; pneumonia; and septicemia, possibly leading to septic shock and death.
If granulocytopenia is caused by an idiosyncratic drug reaction, signs of infection develop abruptly, without slowly progressive fatigue and weakness.
Patients with lymphocytopenia may exhibit enlarged lymph nodes, spleen, and tonsils and signs of an associated disease.
Source: Handbook of Diseases, 2003
These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:
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The symptom information on this page attempts to provide a list of some possible signs and symptoms of Acquired agranulocytosis. This signs and symptoms information for Acquired agranulocytosis has been gathered from various sources, may not be fully accurate, and may not be the full list of Acquired agranulocytosis signs or Acquired agranulocytosis symptoms. Furthermore, signs and symptoms of Acquired agranulocytosis may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Acquired agranulocytosis symptoms.
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