The list of signs and symptoms mentioned in various sources for Aase Smith syndrome includes the 12 symptoms listed below:
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Orofacial cleft defects are divided into two major groups: cleft lip with or without cleft palate or cleft palate only. Cleft of the lip may involve the alveolus (premaxilla) and may extend through the palate (hard and soft). Congenital clefts of the face occur most commonly in the upper lip. They can range from a simple notch to a complete cleft from the lip edge, through the floor of the nostril and through the alveolus. Cleft lip can occur on either or both sides of the midline but rarely along the midline itself. A cleft lip involving only one side is a unilateral cleft lip, and a cleft on both sides of the midline is a bilateral cleft lip. When a bilateral cleft lip involves clefting of the alveolus on both sides of the premaxilla, the premaxilla is separated from the maxilla into a freely moving segment.
A cleft of the palate only may be partial or complete, involving only the soft palate or extending from the soft palate completely through the hard palate. A cleft palate can occur alone or with a cleft lip. Isolated cleft palate is more commonly associated with congenital defects other than isolated cleft lip with or without cleft palate. (See Variations of cleft lip and cleft palate.) The constellation of U-shaped cleft palate, mandibular hypoplasia, and glossoptosis is known as Pierre Robin syndrome, or Robin syndrome. Robin syndrome can occur as an isolated defect or one feature of many different syndromes; therefore, a comprehensive genetic evaluation is suggested for infants with Robin syndrome. Because of the mandibular hypoplasia and glossoptosis, careful evaluation and management of the airway are mandatory for infants with Robin syndrome.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Congenital defects of the face usually occur in the upper lip. They range from a simple notch to a complete cleft from the lip edge through the floor of the nostril, on either side of the midline, but rarely along the midline itself.
A cleft palate may be partial or complete. A complete cleft includes the soft palate, the bones of the maxilla, and the alveolus on one or both sides of the premaxilla. A double cleft runs from the soft palate forward to either side of the nose, separating the maxilla and premaxilla into freely moving segments. In Pierre Robin syndrome, the tongue is displaced due to micrognathia. The tongue prevents the palate from fusing. Glossoptosis coexists with cleft palate.
Isolated cleft palate is more commonly associated with other congenital defects than isolated cleft lip or cleft lip and cleft palate.
Source: Handbook of Diseases, 2003
When considering symptoms of Aase Smith syndrome, it is also important to consider Aase Smith syndrome as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Aase Smith syndrome may cause:
- (Source - Diseases Database)
These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
The symptom information on this page attempts to provide a list of some possible signs and symptoms of Aase Smith syndrome. This signs and symptoms information for Aase Smith syndrome has been gathered from various sources, may not be fully accurate, and may not be the full list of Aase Smith syndrome signs or Aase Smith syndrome symptoms. Furthermore, signs and symptoms of Aase Smith syndrome may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Aase Smith syndrome symptoms.
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